Rabbit Polyclonal (DANRE)tmem208 Antibody

The TMEM208 antibody targets Transmembrane Protein 208. a conserved protein localized to the nuclear envelope and endoplasmic reticulum. In zebrafish (*Danio rerio*, abbreviated DANRE), TMEM208 is implicated in cellular processes such as membrane organization, protein trafficking, and embryonic development. Studies suggest its involvement in maintaining nuclear integrity and regulating cell cycle progression. The DANRE TMEM208 antibody is commonly used in developmental biology research to investigate tissue-specific expression patterns, particularly during early embryogenesis and organogenesis. It has been utilized in techniques like Western blotting, immunohistochemistry, and immunofluorescence to visualize protein distribution in zebrafish models. Recent research links TMEM208 dysfunction to developmental anomalies, including cardiac defects and neural tube malformations, highlighting its role in vertebrate morphogenesis. As zebrafish share significant genetic homology with humans, findings from TMEM208 studies in DANRE may provide insights into human diseases linked to nuclear envelope pathologies. The antibody’s specificity and validation in zebrafish make it a critical tool for exploring TMEM208’s molecular mechanisms and its broader biological significance.