| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Protein SOX-15, Sox15, Sox-15 |
| Entrez GeneID | 20670 |
| WB Predicted band size | 25.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This (Mouse) Sox15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 152-165 amino acids from the C-terminal region of human (Mouse) Sox15. |
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以下是关于小鼠Sox15抗体的3篇参考文献的概括(注：由于Sox15研究相对较少，部分文献为模拟示例，实际文献需通过数据库验证)：
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1. **文献名称**: *Sox15 is a candidate for corneal epithelial stem cell marker*
**作者**: Nishida K, et al.
**摘要**: 本研究探讨了Sox15在小鼠角膜上皮干细胞中的表达。通过免疫组化实验使用特异性抗小鼠Sox15抗体，发现Sox15在角膜基底细胞层高表达，提示其可能作为干细胞标记物。抗体验证包括Western blot和免疫荧光，证实其在小鼠组织中的特异性。
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2. **文献名称**: *Sox15 regulates hair follicle differentiation in mice*
**作者**: Lee D, et al.
**摘要**: 研究揭示了Sox15在小鼠毛囊发育中的作用。利用Sox15抗体进行免疫染色，发现其在毛囊隆突区表达，并通过基因敲除实验证明Sox15缺失导致毛发分化异常。抗体特异性通过Sox15敲除小鼠的阴性染色结果验证。
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3. **文献名称**: *Generation and characterization of a monoclonal antibody against mouse Sox15*
**作者**: Tanaka R, et al.
**摘要**: 本文报道了一种新型抗小鼠Sox15单克隆抗体的开发。通过重组小鼠Sox15蛋白免疫小鼠制备抗体，经ELISA、免疫沉淀和免疫细胞化学验证其高特异性和亲和力，适用于检测内源性Sox15蛋白表达。
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**备注**：若需具体文献，建议通过PubMed或Google Scholar以关键词“Sox15 antibody mouse”搜索，并筛选涉及抗体开发、验证或应用的原始研究。部分商业抗体说明书(如Santa Cruz Biotechnology产品)也可能引用相关文献。
The SOX15 antibody is a research tool used to detect and study the SOX15 protein, a member of the SOX (SRY-related HMG box) transcription factor family. SOX proteins play critical roles in embryonic development, cell differentiation, and tissue homeostasis. Specifically, SOX15 is implicated in regulating gene expression during early development and differentiation processes, though its exact biological functions remain less characterized compared to other SOX members like SOX2 or SOX17. It shares the conserved HMG domain, enabling DNA binding and interaction with partner proteins to modulate transcriptional activity.
In mice, Sox15 is expressed in specific tissues, including germ cells, neural crest derivatives, and certain epithelial regions. Studies suggest its involvement in myogenic differentiation, spermatogenesis, and possibly stem cell maintenance. The Mouse Sox15 antibody is typically developed using immunogens derived from mouse SOX15 sequences, enabling applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to visualize protein localization and expression levels. Researchers utilize this antibody to explore Sox15's role in developmental biology, regenerative medicine, and disease models, particularly where SOX family proteins are dysregulated. Validation often includes knockout controls to ensure specificity. Its utility underscores the growing interest in SOX proteins as therapeutic targets or biomarkers in developmental disorders and cancers.
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