| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B, ppp1cb |
| Entrez GeneID | 108717671;443852 |
| WB Predicted band size | 37.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This XENLA ppp1cb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human XENLA ppp1cb. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于XENLA(*Xenopus laevis*)PPP1CB抗体的模拟参考文献示例(注：以下内容为虚构示例，建议通过PubMed或Google Scholar查询真实文献)：
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1. **文献名称**：*Characterization of PPP1CB in Xenopus laevis Early Embryogenesis*
**作者**：Smith A, et al.
**摘要**：本研究利用针对XENLA PPP1CB的特异性抗体，通过免疫印迹和免疫组化技术，揭示了PPP1CB在非洲爪蟾胚胎早期发育中的动态表达模式，并证明其参与调控细胞周期进程。
2. **文献名称**：*PP1 Phosphatase Subunits in Xenopus Oocyte Maturation: Role of PPP1CB*
**作者**：Chen L, et al.
**摘要**：通过抗体介导的蛋白质功能阻断实验，研究发现PPP1CB在爪蟾卵母细胞成熟过程中与CDK1激酶相互作用，调控减数分裂恢复，提示其参与MAPK信号通路的负向调控。
3. **文献名称**：*Antibody-Based Localization of PPP1CB in Xenopus Neural Tissues*
**作者**：Rodriguez P, et al.
**摘要**：利用特异性抗体进行组织染色，发现PPP1CB在爪蟾胚胎神经管和脑区高表达，支持其在神经分化中的潜在作用，并通过敲降实验验证其对神经元迁移的影响。
4. **文献名称**：*Cross-Species Validation of PPP1CB Antibody Specificity in Xenopus Models*
**作者**：Watanabe K, et al.
**摘要**：本研究系统验证了商用PPP1CB抗体在爪蟾组织裂解液中的特异性，通过siRNA敲除和质谱分析确认其识别目标，为跨物种磷酸酶功能研究提供可靠工具。
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如需真实文献，建议通过以下关键词搜索：
`"Xenopus laevis PPP1CB antibody"`、`"PPP1CB Xenopus phosphatase"`、`"PP1 antibody Xenopus"`
推荐数据库：**PubMed**、**Google Scholar**、**Xenbase**(爪蟾专业数据库)。
The XENLA PPP1CB antibody is designed to target the protein phosphatase 1 catalytic subunit beta (PPP1CB) in *Xenopus laevis* (African clawed frog), a widely used model organism in developmental biology and cellular signaling studies. PPP1CB is a member of the serine/threonine phosphatase family, playing a critical role in regulating diverse cellular processes, including cell cycle progression, glycogen metabolism, and signal transduction by dephosphorylating key substrates. In *Xenopus*, PPP1CB is implicated in early embryonic development, oocyte maturation, and cell division, often interacting with regulatory subunits to direct its substrate specificity and subcellular localization.
This antibody is typically generated in host species (e.g., rabbit or mouse) using immunogens derived from conserved regions of the *Xenopus* PPP1CB protein. It is validated for applications such as Western blotting, immunohistochemistry, or immunofluorescence to detect endogenous PPP1CB expression in *Xenopus* tissues, oocytes, or embryos. Researchers utilize this tool to investigate PPP1CB's functional roles in signaling pathways (e.g., Wnt or MAPK) and its contribution to developmental mechanisms. As PPP1 isoforms (e.g., PPP1CA, PPP1CC) share high homology, specificity validation via knockout controls or peptide-blocking assays is essential to ensure accurate detection. The antibody serves as a key reagent in studies linking phosphatase activity to *Xenopus* embryogenesis and disease-related pathways.
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