首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal ZSCAN5C(Center) Antibody

  • 中文名: ZSCAN5C(Center)抗体
  • 别    名: Zinc finger and SCAN domain-containing protein 5C, ZSCAN5C
货号: IPDX32252
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesZinc finger and SCAN domain-containing protein 5C, ZSCAN5C
WB Predicted band size55.7kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis ZSCAN5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-162 amino acids from the Central region of human ZSCAN5C.
FormulationPurified antibody in PBS with 0.05% sodium azide.

+ +

参考文献

以下是关于ZSCAN5C(Center)抗体的虚构参考文献示例(仅供示例用途,非真实文献):

---

1. **文献名称**:ZSCAN5C regulates pluripotency in human embryonic stem cells

**作者**:Smith A, et al.

**摘要**:本研究利用Center公司生产的ZSCAN5C抗体,通过ChIP-seq和免疫荧光技术,揭示了ZSCAN5C在维持人类胚胎干细胞多能性中的关键作用,发现其通过调控特定靶基因的染色质可及性影响分化进程。

2. **文献名称**:ZSCAN5C overexpression links to genomic instability in cancer

**作者**:Lee B, et al.

**摘要**:通过Western blot(使用Center的ZSCAN5C抗体)和功能实验,本文证明ZSCAN5C在多种癌症中异常高表达,可能通过干扰DNA修复机制导致基因组不稳定,提示其作为肿瘤治疗潜在靶点。

3. **文献名称**:Characterization of ZSCAN5C antibody specificity in primate models

**作者**:Garcia R, et al.

**摘要**:本文系统评估了Center公司ZSCAN5C抗体的特异性,证实其在灵长类细胞系中可特异性识别内源性ZSCAN5C蛋白,为后续研究提供了可靠的实验工具验证。

4. **文献名称**:ZSCAN5C interacts with telomeric chromatin in cellular senescence

**作者**:Chen H, et al.

**摘要**:结合免疫共沉淀(使用Center抗体)和测序分析,研究发现ZSCAN5C通过结合端粒区域调控细胞衰老进程,揭示其在衰老相关疾病中的潜在调控机制。

---

注:以上内容为模拟生成,实际文献需通过学术数据库(如PubMed、Web of Science)检索确认。若研究内容较新或较冷门,建议直接联系抗体供应商获取引用文献。

背景信息

ZSCAN5C (Center) antibody targets the central region of the Zinc Finger and SCAN Domain-Containing Protein 5C (ZSCAN5C), a transcription factor belonging to the SCAN family. This protein is characterized by its conserved SCAN domain, which mediates protein-protein interactions, and C-terminal zinc finger motifs that likely bind DNA to regulate gene expression. ZSCAN5C is implicated in transcriptional regulation, particularly in processes like cell differentiation, proliferation, and embryonic development, though its precise biological roles remain under investigation.

The antibody is commonly used to detect endogenous ZSCAN5C protein levels in research applications such as Western blotting (WB), immunofluorescence (IF), and immunohistochemistry (IHC). Its specificity for the central region ensures recognition of full-length isoforms, aiding in studies exploring ZSCAN5C's nuclear localization and function. Research suggests ZSCAN5C may play roles in cancer biology, with aberrant expression observed in certain malignancies, though mechanistic insights are still emerging. Validated for reactivity in human and possibly other mammalian models, this tool helps elucidate ZSCAN5C's interaction networks and regulatory pathways, contributing to broader understanding of SCAN family proteins in health and disease.

客户数据及评论

折叠内容

大包装询价

×