Rabbit Polyclonal DPCR1(Center) Antibody

The DPCR1 (Center) antibody is a reagent designed to detect the DPCR1 protein, which is encoded by the *DPCR1* gene (Deleted in Primary Ciliary Dyskinesia and Rhinitis 1). While the precise biological function of DPCR1 remains under investigation, studies suggest its potential involvement in ciliary function and mucosal immunity. The gene is located in a genomic region associated with primary ciliary dyskinesia (PCD), a genetic disorder characterized by impaired ciliary motility, leading to chronic respiratory infections and situs inversus. DPCR1's expression has been observed in ciliated epithelial cells, hinting at a role in cilia structure or signaling. The DPCR1 (Center) antibody is commonly used in research applications such as immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting (WB) to study protein localization and expression patterns in tissues or cell lines. Its specificity is often validated using knockout controls or siRNA-mediated knockdown. Researchers utilize this antibody to explore DPCR1's potential contributions to ciliopathies, chronic inflammatory conditions, or its interaction with other ciliary proteins. However, the antibody's utility may depend on proper validation in specific experimental models, as cross-reactivity with unrelated epitopes has not been fully ruled out in all contexts.