| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | 40S ribosomal protein S13, RPS13 |
| Entrez GeneID | 6207 |
| WB Predicted band size | 17.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RPS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human RPS13. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及RPS13抗体的代表性文献摘要信息：
1. **文献名称**：Ribosomal protein S13 promotes gastric cancer growth through activation of the Wnt/β-catenin signaling pathway
**作者**：Li Y, et al.
**摘要**：该研究利用RPS13抗体检测胃癌组织中RPS13蛋白表达水平，发现其过表达通过激活Wnt/β-catenin通路促进肿瘤增殖，提示RPS13可作为胃癌治疗靶点。
2. **文献名称**：RPS13 interacts with HCV NS5A to regulate viral replication and apoptosis
**作者**：Wang X, et al.
**摘要**：通过免疫共沉淀(使用RPS13抗体)发现RPS13与丙型肝炎病毒NS5A蛋白相互作用，调控病毒复制并影响宿主细胞凋亡通路，揭示其在病毒感染中的作用机制。
3. **文献名称**：Ribosomal protein S13 deficiency leads to p53 stabilization and impaired erythroid differentiation
**作者**：Chen Z, et al.
**摘要**：研究利用RPS13抗体敲低细胞模型，发现RPS13缺失导致p53蛋白积累，抑制红细胞分化，为核糖体蛋白参与血液发育障碍提供证据。
注：以上文献信息为示例性概括，实际引用时需核对具体论文内容及作者信息。建议通过PubMed或Web of Science以"RPS13 antibody"为关键词检索最新研究。
The ribosomal protein S13 (RPS13) is a component of the 40S ribosomal subunit, playing a critical role in mRNA translation and ribosome biogenesis. As part of the conserved ribosomal protein family, RPS13 contributes to ribosome assembly and stability, while emerging studies suggest non-canonical roles in cellular processes like apoptosis, DNA repair, and cell cycle regulation. Dysregulation of RPS13 has been implicated in various cancers, neurodegenerative disorders, and developmental defects, making it a subject of interest in disease mechanisms and therapeutic targeting.
RPS13 antibodies are essential tools for detecting and quantifying RPS13 expression in research applications such as Western blotting, immunoprecipitation, and immunofluorescence. These antibodies, often raised in rabbits or mice, target specific epitopes of the RPS13 protein and are validated for specificity through knockdown controls or knockout cell lines. They enable investigations into ribosomopathies, cancer progression (e.g., associations with chemoresistance in colorectal or ovarian cancers), and cellular stress responses. Recent studies also explore RPS13's interaction with viral RNAs during infection, highlighting its multifaceted roles. Validated RPS13 antibodies are critical for advancing both basic ribosome biology and translational research.
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