WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008 |
Entrez GeneID | 9787 |
WB Predicted band size | 95.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This DLG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DLG7. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
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以下是关于DLG7 (N-term)抗体的模拟参考文献示例(仅供参考,具体文献需通过学术数据库检索确认):
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1. **文献名称**:*DLG7 Expression in Mitotic Progression: Role of N-terminal Domain in Spindle Pole Localization*
**作者**:Zhang Y, et al.
**摘要**:该研究使用DLG7 (N-term)抗体进行免疫荧光染色,发现DLG7的N端结构域对定位到有丝分裂纺锤体极体至关重要,敲低DLG7导致染色体排列异常,提示其在细胞分裂中的功能依赖性。
2. **文献名称**:*DLG7 as a Prognostic Marker in Ovarian Cancer: Immunohistochemical Analysis*
**作者**:Chen L, et al.
**摘要**:通过DLG7 (N-term)抗体的免疫组化实验,证实DLG7在卵巢癌组织中高表达,且与患者生存率负相关,提示其可能作为癌症治疗的潜在靶点。
3. **文献名称**:*Characterization of DLG7 Antibody Specificity Using CRISPR-Cas9 Knockout Validation*
**作者**:Abcam Technical Report
**摘要**:该技术报告验证了DLG7 (N-term)抗体的特异性,通过CRISPR敲除DLG7的细胞系进行Western blot和免疫沉淀实验,证明抗体在多种实验条件下的可靠性。
4. **文献名称**:*DLG7 Interaction with Aurora Kinase B in Regulating Mitotic Checkpoint*
**作者**:Wang H, et al.
**摘要**:利用DLG7 (N-term)抗体进行共免疫沉淀实验,发现DLG7与Aurora激酶B在维持有丝分裂检查点中的相互作用,为靶向治疗提供了分子机制依据。
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**建议**:实际文献可通过PubMed、Google Scholar或抗体供应商(如CST、Abcam)的“引用文献”板块检索,关键词包括“DLG7 antibody”、“DLG7 N-terminal”或“DLG7 mitosis”。
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