| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 1/50-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | ESP2; HED2; ZYX; Zyxin2 |
| Entrez GeneID | 7791 |
| WB Predicted band size | Calculated MW: 61 kDa; Observed MW: 78 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthesized peptide derived from human Zyxin |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是3篇关于ZYX(Zyxin)抗体的模拟参考文献示例(内容为虚构，仅供格式参考)：
---
1. **文献名称**: *Zyxin Antibody-Based Detection of Focal Adhesion Dynamics in Cancer Cell Migration*
**作者**: Chen L, et al.
**摘要**: 本研究利用ZYX特异性抗体，通过免疫荧光和Western blot技术，揭示了Zyxin在乳腺癌细胞迁移过程中对黏着斑动态组装的调控作用，提示其可能成为抑制转移的潜在靶点。
2. **文献名称**: *Interaction between Zyxin and LPP in Smooth Muscle Cells: A Co-IP Study Using Anti-ZYX Antibody*
**作者**: Müller S, et al.
**摘要**: 通过ZYX抗体的免疫共沉淀(Co-IP)实验，证实了Zyxin与LPP蛋白在血管平滑肌细胞机械应力响应中的直接相互作用，为理解细胞骨架重塑机制提供证据。
3. **文献名称**: *Developmental Expression of Zyxin in Zebrafish Embryos: An Immunohistochemical Analysis*
**作者**: Tanaka K, et al.
**摘要**: 采用ZYX多克隆抗体对斑马鱼胚胎进行免疫组化分析，发现Zyxin在体节形成和神经嵴细胞迁移中的时空特异性表达，提示其在胚胎发育中的关键角色。
---
**提示**：实际文献建议通过PubMed或Google Scholar检索关键词“Zyxin antibody application”、“ZYX immune localization”等，并筛选近5年高被引论文。
ZYX antibody targets zyxin, a cytoskeletal protein involved in cell adhesion and migration. Zyxin, encoded by the ZYX gene in humans, is a LIM domain-containing protein localized at focal adhesions and cell-cell junctions. It interacts with components of the actin cytoskeleton, such as α-actinin and vinculin, facilitating mechanotransduction and maintaining structural integrity during cellular movement. Zyxin also shuttles to the nucleus under stress, potentially regulating gene expression related to cell survival or apoptosis.
ZYX antibodies are widely used in research to study cell motility, wound healing, and cancer metastasis. In immunofluorescence, they highlight focal adhesion dynamics, while Western blotting confirms zyxin expression levels across tissues. These antibodies have revealed zyxin's role in cardiovascular development, as knockout models exhibit heart defects. Commercially available ZYX antibodies are typically raised in rabbits or mice, with specificity validated via knockout cell lines. Recent studies explore zyxin's involvement in fibroblast activation during fibrosis and its potential as a biomarker in certain carcinomas. Proper validation remains crucial due to cross-reactivity risks with other LIM proteins like LPP or TRIP6.
×
