关键信息
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基因名
ZFHX1B
- 应用
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别名
ZEB2; SIP1; SIP-1; SMADIP1; SIP1; Zinc Finger E-Box Binding Homeobox 2; SMAD Interacting Protein 1
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9R0G7
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表达区间
Gln962~Glu1215
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分子量
22kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ZFHX1B, also known as Zinc Finger Homeobox 1B, is a transcription factor that belongs to the homeobox gene family, playing a critical role in development and cellular processes. It is characterized by its zinc-finger motifs and homeodomain, which facilitate DNA binding and interaction with other transcriptional regulators. Research into ZFHX1B has gained prominence due to its association with various developmental disorders, particularly the 18q deletion syndrome, which is characterized by cognitive impairment, growth deficiencies, and congenital malformations. Understanding the molecular mechanisms and pathways regulated by ZFHX1B is essential for elucidating its role in normal development and disease pathogenesis. Additionally, studies have indicated that ZFHX1B may be involved in cancer progression, highlighting its potential as a therapeutic target. The recombinant protein form of ZFHX1B is particularly valuable for investigations into its functional characteristics, interaction with other proteins, and regulatory networks. By producing ZFHX1B as a recombinant protein, researchers can conduct in vitro assays to determine its DNA-binding capabilities and its influence on gene expression. Overall, the study of ZFHX1B recombinant protein is crucial for advancing our understanding of its biological functions and implications in human health and disease.
