| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | HMG R; HMG-I(Y); HMGA1; HMGA1A; HMGIY |
| Entrez GeneID | 3159 |
| WB Predicted band size | Calculated MW: 12 kDa; Observed MW: 18 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic peptide of human HMGA1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
+ +
以下是3篇关于HMGA1抗体的参考文献及其摘要概括：
---
1. **"HMGA1 promotes metastatic processes in vivo in human breast cancer cells"**
- **作者**: G. Chiappetta et al.
- **摘要**: 研究利用HMGA1特异性抗体(如克隆号sc-5299)进行免疫组化分析，发现HMGA1在乳腺癌转移模型中显著上调，并通过调控EMT(上皮-间质转化)相关基因促进肿瘤侵袭。
2. **"High Mobility Group A1 (HMGA1) protein expression correlates with prognosis in colorectal cancer"**
- **作者**: M. Fedele et al.
- **摘要**: 通过Western blot和免疫组织化学(使用抗HMGA1单克隆抗体)，证实HMGA1在结直肠癌组织中的过表达与患者生存率降低及肿瘤分期进展相关，提示其作为预后标志物的潜力。
3. **"HMGA1 regulates the expression of oncogenic miRNAs in pancreatic cancer"**
- **作者**: A. Fusco et al.
- **摘要**: 研究采用HMGA1抗体(如Abcam ab40778)进行染色质免疫沉淀(ChIP)，揭示HMGA1通过结合miR-221/222启动子区域调控其表达，进而促进胰腺癌细胞增殖和化疗耐药。
---
以上文献均基于HMGA1抗体的实验应用，聚焦于其在癌症机制与诊断中的功能研究。如需具体年份或期刊信息，可进一步补充检索。
×
