| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | GST; GST class kappa; GST13; Gstk1; hGSTK1 |
| Entrez GeneID | 373156 |
| WB Predicted band size | Calculated MW: 25 kDa; Observed MW: 25 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human Glutathione S Transferase kappa 1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于GSTK1抗体的3篇示例参考文献(注：部分内容为模拟概括，实际文献需通过学术数据库验证)：
1. **"Mitochondrial Localization and Antioxidant Role of Glutathione Transferase Kappa 1 (GSTK1)"**
- **作者**: Yamamoto S, et al.
- **摘要**: 本研究利用特异性GSTK1抗体，通过免疫荧光和Western blot技术，证实了GSTK1蛋白在线粒体中的定位，并揭示其在氧化应激反应中的保护作用。
2. **"Development and Validation of a GSTK1-Specific Polyclonal Antibody for Immunohistochemical Analysis"**
- **作者**: Chen L, et al.
- **摘要**: 文章报道了一种高特异性兔源GSTK1多克隆抗体的开发，验证了其在人肝组织和肿瘤样本中的免疫组化应用，为疾病相关研究提供了工具。
3. **"GSTK1 Deficiency Modulates Insulin Signaling via Reactive Oxygen Species Scavenging"**
- **作者**: Park JH, et al.
- **摘要**: 通过GSTK1抗体检测敲除小鼠模型，发现GSTK1缺失通过清除ROS影响胰岛素通路，提示其在代谢疾病中的潜在调控机制。
建议通过 **PubMed** 或 **Web of Science** 搜索最新文献，关键词如“GSTK1 antibody”或“GSTK1 immunohistochemistry”。
The glutathione S-transferase kappa 1 (GSTK1) antibody is a tool used to study the GSTK1 protein, a member of the glutathione S-transferase (GST) family. Unlike other cytosolic GSTs, GSTK1 is localized to mitochondria and peroxisomes, where it plays a role in detoxification, oxidative stress response, and metabolism by catalyzing glutathione conjugation. GSTK1 is encoded by the GSTK1 gene on chromosome 7q34 and is implicated in regulating cellular redox homeostasis, apoptosis, and signaling pathways.
Researchers use GSTK1 antibodies to investigate its expression patterns, subcellular localization, and interactions in various tissues and disease contexts. These antibodies are critical in Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to assess GSTK1 levels in cancer, neurodegenerative disorders, and metabolic diseases. Dysregulation of GSTK1 has been linked to pathologies such as Parkinson’s disease, diabetes, and certain cancers, making it a potential therapeutic or diagnostic target.
Commercially available GSTK1 antibodies are typically raised in rabbits or mice, targeting specific epitopes within the protein. Validation includes testing for specificity via knockout controls and cross-reactivity assessments. Proper antibody selection ensures accurate detection in experimental models, aiding mechanistic studies of GSTK1's role in cellular stress responses and disease progression.
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