首页 / 产品 / 抗体 / 一抗

Rabbit Monoclonal AER61 Antibody

  • 中文名： AER61抗体
  • 别    名： Extracellular O-linked N-acetylglucosamine transferase
货号: IPDX21015
Price： ￥1280
数量：
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesExtracellular O-linked N-acetylglucosamine transferase
Entrez GeneID285203
WB Predicted band sizeCalculated MW: 62 kDa; Observed MW: 62 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Rat
ImmunogenRecombinant protein of human AER61
FormulationPurified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

+ +

参考文献

以下是关于AER61抗体的虚构参考文献示例(基于常见研究场景假设，实际文献需通过学术数据库验证)：

1. **文献名称**: *AER61: A Novel Monoclonal Antibody Targeting EGFRvIII in Glioblastoma*

**作者**: Smith J, et al.

**摘要**: 本研究报道了AER61抗体的开发，其特异性靶向胶质母细胞瘤中EGFRvIII突变体。实验显示，AER61通过抑制EGFRvIII信号通路显著抑制肿瘤生长，并在小鼠模型中延长生存期。

2. **文献名称**: *Preclinical Evaluation of AER61 in Triple-Negative Breast Cancer Models*

**作者**: Wang L, et al.

**摘要**: 研究评估了AER61在三阴性乳腺癌中的疗效，发现其通过结合肿瘤细胞表面过表达的HER2蛋白，诱导抗体依赖性细胞毒性(ADCC)，并在联合化疗中表现出协同作用。

3. **文献名称**: *Mechanisms of Resistance to AER61 in Colorectal Cancer*

**作者**: Rodriguez M, et al.

**摘要**: 该文献探讨了结直肠癌对AER61的耐药机制，发现MET通路激活和肿瘤微环境中的免疫抑制细胞(如TAMs)是导致耐药的关键因素，并提出联合靶向治疗策略。

4. **文献名称**: *Structural Characterization of AER61 and Its Epitope Mapping*

**作者**: Kim H, et al.

**摘要**: 通过X射线晶体学解析了AER61与靶抗原的结合表位，揭示了其高亲和力的结构基础，为优化抗体药物设计提供了理论依据。

**注意**：以上内容为模拟生成，实际文献需通过PubMed、Google Scholar等平台检索。若AER61为特定研究中的抗体，建议结合具体研究背景或抗体编号进一步查询。

背景信息

The AER61 antibody is a research tool developed to target specific epitopes associated with cellular processes, though its exact antigen remains less characterized in public literature. Typically used in molecular biology and biomedical research, it is likely a monoclonal antibody produced in hosts like mice or rabbits, designed for applications such as Western blotting (WB), immunohistochemistry (IHC), or immunofluorescence (IF). AER61 may be linked to studies involving cancer, neurodegeneration, or immune regulation, depending on its target protein. Such antibodies are often pivotal in identifying biomarkers, elucidating signaling pathways, or validating therapeutic targets. While specific details on AER61’s development and validation are scarce in open-access databases, antibodies of this type generally undergo rigorous testing for specificity, affinity, and cross-reactivity. Researchers might employ it to investigate protein expression patterns, subcellular localization, or functional roles in disease models. Its utility could extend to preclinical studies, aiding in drug discovery or mechanistic explorations. As with many research antibodies, reproducibility and batch consistency are critical considerations. Further context would require access to proprietary data or peer-reviewed studies explicitly referencing AER61.

客户数据及评论

折叠内容

大包装询价

×