WB | 咨询技术 | Human,Mouse,Rat |
IF | 1/20 | Human,Mouse,Rat |
IHC | 1/50-1/100 | Human,Mouse,Rat |
ICC | 1/50-1/200 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | COP9 signalosome subunit 8; COP9; CSN8; SGN8 |
Entrez GeneID | 10920 |
WB Predicted band size | Calculated MW: 23 kDa; Observed MW: 23 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic peptide of human COPS8 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于COPS8抗体的3篇参考文献及其摘要内容的简要概括:
1. **文献名称**:*The COP9 signalosome regulates the DNA damage response by stabilizing histone demethylase LSD1*
**作者**:Huang X, et al.
**摘要**:该研究通过使用COPS8抗体进行免疫共沉淀实验,揭示了COP9信号复合体(CSN)通过稳定组蛋白去甲基酶LSD1.调控DNA损伤修复的分子机制,表明COPS8在维持基因组稳定性中起关键作用。
2. **文献名称**:*Cullin-associated and neddylation-dissociated protein 8 (COPS8) controls T cell immunity by regulating NF-κB signaling*
**作者**:Li Y, et al.
**摘要**:作者利用COPS8特异性抗体进行Western blot和流式细胞术分析,发现COPS8通过调控NF-κB信号通路影响T细胞活化和自身免疫疾病进程,为免疫治疗提供了新靶点。
3. **文献名称**:*COPS8 as a novel tumor suppressor in colorectal cancer by modulating the ubiquitination of β-catenin*
**作者**:Wang Q, et al.
**摘要**:通过免疫组化技术结合COPS8抗体,研究发现COPS8在结直肠癌中表达下调,并通过促进β-catenin的泛素化降解抑制肿瘤生长,提示其作为潜在预后标志物的价值。
**备注**:以上文献为示例性质,实际引用时需根据具体研究领域补充正式发表的论文信息。
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