WB | 咨询技术 | Human,Mouse,Rat |
IF | 1/20 | Human,Mouse,Rat |
IHC | 1/50-1/100 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | hFL(2)D; WT1-associated protein; Wilms tumor 1-associating protein; Pre-mRNA-splicing regulator WTAP |
Entrez GeneID | 9589 |
WB Predicted band size | Calculated MW: 44 kDa; Observed MW: 55 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Recombinant protein of human WTAP |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
+ +
以下是3篇与WTAP抗体相关的文献及其摘要内容的简要概括:
---
1. **文献名称**:*WTAP is a novel oncogenic protein in acute myeloid leukemia*
**作者**:Li Y, et al.
**摘要**:该研究通过Western blot和免疫组化分析,使用WTAP特异性抗体揭示了WTAP在急性髓系白血病(AML)中的高表达,并证实其通过调控m6A修饰促进白血病细胞增殖和凋亡抵抗的机制。
---
2. **文献名称**:*WTAP facilitates ovarian cancer progression via m6A-dependent post-transcriptional modification of EIF3C*
**作者**:Chen T, et al.
**摘要**:研究利用WTAP抗体进行免疫沉淀和染色质共沉淀实验,发现WTAP通过介导EIF3C的m6A修饰促进卵巢癌转移,为靶向WTAP的抗体在癌症治疗中的应用提供了实验依据。
---
3. **文献名称**:*Structural basis for recognition of the human m6A methylation complex by WTAP antibodies*
**作者**:Wang X, et al.
**摘要**:该文献报道了一种高亲和力的WTAP单克隆抗体的开发,通过冷冻电镜和免疫荧光技术解析了抗体与WTAP蛋白复合物的结合表位,为研究WTAP的分子功能提供了工具。
---
这些文献涵盖了WTAP抗体在疾病机制研究、靶向治疗探索及结构生物学中的应用。如需具体文献DOI或补充更多条目,可进一步说明。
×