关键信息
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基因名
ADORA3
- 应用
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别名
A3AR; AD026
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P28647
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表达区间
Lys287~Glu320
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分子量
14kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ADORA3 (Adenosine A3 receptor) is a member of the adenosine receptor family, which plays a pivotal role in various physiological processes and pathophysiological conditions. As a G protein-coupled receptor, ADORA3 is involved in modulating immune responses, inflammation, and cardioprotection, making it a potential therapeutic target for diseases such as cancer, cardiovascular disorders, and neurodegenerative diseases. The receptor's unique signaling pathways, mediated through its interaction with adenosine, have garnered significant interest in pharmacology and drug development. Recent research has focused on the characterization of recombinant ADORA3 proteins to elucidate their functional properties and to facilitate the screening of novel ligands and drugs. By producing ADORA3 in various expression systems, researchers aim to study its structure-function relationships and interactions with signaling partners. The development of ADORA3 recombinant proteins enhances our understanding of how this receptor can be modulated in a therapeutic context, paving the way for innovative treatments targeting adenosine signaling pathways. This research is critical for uncovering the role of ADORA3 in disease mechanisms and for developing effective pharmacological agents that can specifically target this receptor to improve patient outcomes.
