关键信息
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基因名
A2BP1
- 应用
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别名
RBFOX1; FOX1; HRNBP1; A2-BP1; Hexaribonucleotide Binding Protein 1; RNA Binding Protein,Fox-1 Homolog 1
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
D3ZSL1
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表达区间
Asp149~Ser399
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分子量
32kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
A2BP1, or Ataxin-2-binding protein 1, is a member of the RNA-binding protein family that plays a crucial role in post-transcriptional regulation of gene expression. Research into A2BP1 has gained momentum due to its implications in various neurological disorders and developmental processes. Its involvement in key cellular functions, such as mRNA splicing, stability, and transport, underscores its significance in the nervous system, where it influences neuronal differentiation and synaptic function. Mutations and dysregulation of A2BP1 have been linked to diseases, including autism spectrum disorders and other neurodevelopmental conditions, indicating its potential as a therapeutic target. Recent studies have focused on understanding the structural properties and molecular mechanisms of A2BP1, shedding light on its interactions with RNA and other proteins. Investigating A2BP1's functional roles in neuronal context and its pathways could unveil new insights into its contribution to brain development and disease, positioning it as a key player in both basic neuroscience research and clinical applications.
