| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Sulfite oxidase; Suox;;SUOX |
| WB Predicted band size | 60 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthesized peptide derived from human SUOX |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是3篇与SUOX(亚硫酸盐氧化酶)抗体相关的文献示例(注：文献为示例性内容，非真实存在)：
1. **文献名称**：*"Characterization of a Novel Monoclonal Antibody Against Human Sulfite Oxidase"*
**作者**：Smith J, et al.
**摘要**：研究报道了一种新型单克隆抗体的开发，该抗体特异性识别人源SUOX蛋白，并通过免疫印迹和免疫组化验证其在组织样本中的表达，为亚硫酸盐氧化酶缺乏症的诊断提供了工具。
2. **文献名称**：*"SUOX Deficiency: Immunohistochemical Detection in Patient Tissues Using Custom Antibodies"*
**作者**：Lee H, et al.
**摘要**：通过构建SUOX基因敲除小鼠模型，利用特异性抗体分析SUOX蛋白在肝脏和脑组织中的表达缺失，揭示了其在硫代谢异常相关神经退行性疾病中的潜在作用。
3. **文献名称**：*"Development of a Polyclonal Antibody for Sulfite Oxidase Activity Assay in Plant Systems"*
**作者**：Garcia R, et al.
**摘要**：研究开发了一种多克隆抗体，用于检测植物中亚硫酸盐氧化酶的活性，发现SUOX在植物抗逆响应中的新功能，拓展了其在非动物模型中的应用场景。
(注：以上为基于SUOX抗体研究领域的典型方向模拟生成的文献，实际文献需通过PubMed或Web of Science等平台检索确认。)
The sulfite oxidase (SUOX) antibody is a crucial tool in studying the enzyme sulfite oxidase, which plays a vital role in sulfur metabolism. Sulfite oxidase, encoded by the *SUOX* gene, catalyzes the oxidation of sulfite to sulfate, a critical step in detoxifying sulfite—a byproduct of amino acid and lipid metabolism. Deficiencies in SUOX activity, caused by genetic mutations or molybdenum cofactor defects, lead to severe neurological disorders and early mortality, underscoring the enzyme's importance in cellular homeostasis.
SUOX antibodies are primarily used in research to detect and quantify SUOX protein expression in tissues, aiding in the diagnosis of inherited sulfite oxidase deficiency and related metabolic disorders. They are also employed in studying mitochondrial function, as SUOX is localized to the mitochondrial intermembrane space. Additionally, these antibodies help explore SUOX's role in pathologies beyond genetic defects, such as its potential involvement in oxidative stress responses, cancer progression, and neurodegenerative diseases.
Developed through immunization with purified SUOX protein or specific peptide sequences, these antibodies are validated for applications like Western blotting, immunohistochemistry, and immunofluorescence. Recent studies also utilize SUOX antibodies to investigate post-translational modifications or interactions with other metabolic enzymes, offering insights into broader regulatory networks. Their specificity and reliability make SUOX antibodies indispensable for both basic research and clinical investigations into sulfur metabolism disorders.
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