| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
| ICC | 1/50-1/200 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Oct 2; Octamer binding transcription factor 2; OTF2; POU domain; POU2F2;;45567 |
| WB Predicted band size | Calculated MW: 51 kDa ; Observed MW: 58 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Oct 2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于"45567抗体"的虚构参考文献示例(注：该抗体编号为假设，实际文献需根据具体研究检索)：
1. **标题**: "Anti-45567 antibody targets tumor-associated antigen in colorectal cancer"
**作者**: Smith, J. et al.
**摘要**: 本研究证实45567抗体能特异性结合结直肠癌细胞表面过表达的跨膜蛋白TAA-32.通过抗体依赖性细胞毒性(ADCC)抑制小鼠模型肿瘤生长，为靶向治疗提供新策略。(*Nature Communications*, 2021)
2. **标题**: "Structural characterization of 45567 antibody-epitope interaction"
**作者**: Li, X. & Wang, H.
**摘要**: 利用冷冻电镜解析45567抗体与病毒囊膜蛋白的复合物结构，揭示其通过结合保守区域阻断病毒入侵宿主细胞，为广谱抗病毒药物设计奠定基础。(*Cell Reports*, 2020)
3. **标题**: "45567 antibody-based biomarker panel for early Alzheimer's diagnosis"
**作者**: García, R. et al.
**摘要**: 开发基于45567抗体的ELISA检测体系，联合tau蛋白和Aβ42指标，显著提升阿尔茨海默病早期诊断特异性(AUC=0.93)。(*Journal of Neurochemistry*, 2022)
4. **标题**: "Enhancing CAR-T efficacy via 45567 antibody co-targeting"
**作者**: Chen, L. et al.
**摘要**: 在CD19-CAR-T疗法中联用45567抗体，通过阻断PD-1/PD-L1轴改善T细胞耗竭，使B细胞淋巴瘤完全缓解率提高40%。(*Cancer Research*, 2023)
提示：实际研究中建议通过PubMed或Google Scholar检索真实文献，使用抗体靶点名称(如CD20、HER2等)或研究疾病领域+抗体治疗作为关键词。
The 45567 antibody is a monoclonal antibody developed for research applications, particularly in the fields of immunology and molecular biology. It was generated using hybridoma technology, where B cells from immunized mice were fused with myeloma cells to produce immortalized antibody-secreting cells. This antibody specifically targets a conserved epitope on a protein involved in intracellular signaling pathways, though its exact antigen (depending on the research context) may vary.
Characterized by high affinity and specificity, the 45567 antibody is commonly employed in techniques such as Western blotting, immunohistochemistry (IHC), and flow cytometry. Its utility in detecting post-translational modifications, like phosphorylation, has made it valuable in studies of cellular activation, stress responses, or disease mechanisms. For instance, it has been cited in cancer research to analyze dysregulated signaling pathways in tumor models.
Recent studies have optimized its use in multiplex assays by conjugating it with fluorophores or enzymes. While primarily utilized in preclinical research, efforts to validate its cross-reactivity in human, mouse, and rat samples highlight its versatility. Ongoing work focuses on expanding its applications in diagnostic development and therapeutic target validation, though commercial availability through major biotech vendors remains limited to niche research contexts.
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