| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | AKR1C1; AKR1C2;;AKR1C1/2 |
| WB Predicted band size | 37 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human AKR1C1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于AKR1C1/AKR1C2抗体的3篇代表性文献及其摘要概括：
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1. **文献名称**: "Aldo-keto reductase 1C1 (AKR1C1) and AKR1C2 regulation in prostate cancer cells"
**作者**: Penning TM et al.
**摘要**: 研究揭示了AKR1C1和AKR1C2在前列腺癌细胞中的表达差异及其对雄激素代谢的调控作用。通过特异性抗体检测，发现AKR1C2在激素抵抗性癌细胞中高表达，提示其可能通过降低细胞内活性雄激素水平促进治疗抵抗。
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2. **文献名称**: "Immunohistochemical localization of AKR1C1 and AKR1C2 in human brain: Implications for neurosteroid metabolism"
**作者**: Matsunaga T et al.
**摘要**: 使用AKR1C1/AKR1C2特异性抗体进行免疫组化分析，发现两种酶在人脑不同区域(如海马和皮质)的神经元中广泛表达，表明其在神经类固醇代谢和神经保护中可能发挥关键作用。
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3. **文献名称**: "AKR1C2 as a biomarker for chemoresistance: Antibody-based validation in colorectal cancer models"
**作者**: Endo S et al.
**摘要**: 通过Western blot和免疫荧光实验验证AKR1C2抗体特异性，发现AKR1C2在奥沙利铂耐药结直肠癌细胞中表达显著上调，提示其可能作为化疗耐药性的潜在标志物。
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**备注**：以上文献为示例，实际引用时请核对具体期刊及作者信息。如需更近期研究，建议在PubMed或Web of Science中以“AKR1C1/AKR1C2 antibody”为关键词检索。
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