| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 1/20-1/50 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | ILF 2; MGC8391; NF45;;ILF2 |
| WB Predicted band size | 43 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human ILF2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是3篇与ILF2抗体相关的参考文献示例(注：内容为虚构，用于示例格式)：
1. **文献名称**：*ILF2 regulates DNA repair and chemoresistance in ovarian cancer via homologous recombination*
**作者**：Li, X., Zhang, Y., & Wang, Q.
**摘要**：本研究通过免疫共沉淀(Co-IP)和Western blot分析，发现ILF2抗体特异性识别卵巢癌细胞中ILF2蛋白，并证实其通过调控BRCA1介导的同源重组修复通路增强顺铂耐药性。
2. **文献名称**：*NF45/ILF2 interacts with viral RNA to promote hepatitis B virus replication*
**作者**：Chen, L., Liu, H., & Wei, F.
**摘要**：利用ILF2抗体进行RNA免疫沉淀(RIP)实验，发现ILF2直接结合HBV RNA，促进病毒核心颗粒组装，提示其在乙肝病毒生命周期中的关键作用。
3. **文献名称**：*ILF2 stabilizes c-Myc mRNA in colorectal cancer by recruiting RNA-binding proteins*
**作者**：Kim, S., Park, J., & Lee, M.
**摘要**：通过siRNA敲低和ILF2抗体介导的免疫荧光染色，揭示ILF2通过结合c-Myc mRNA 3'UTR并招募HuR蛋白，稳定致癌基因表达，促进结直肠癌进展。
(注：以上文献及作者为示例性虚构内容，实际引用需以真实发表文献为准。)
**Background of ILF2 Antibody**
ILF2 (Interleukin Enhancer Binding Factor 2), also known as NF45. is a multifunctional protein involved in transcriptional regulation, RNA processing, and DNA repair. It forms a stable heterodimer with ILF3 (NF90), critical for stabilizing mRNA and regulating gene expression. ILF2 plays roles in immune response, cell cycle progression, and apoptosis, and is implicated in cancer, viral infection, and autoimmune diseases.
ILF2 antibodies are essential tools for detecting and analyzing ILF2 in research. These antibodies, often polyclonal or monoclonal, enable techniques like Western blotting, immunoprecipitation, and immunofluorescence to study ILF2's expression, localization, and interactions. Specific ILF2 antibodies target epitopes in conserved regions, ensuring cross-reactivity in human, mouse, and rat models.
In disease contexts, ILF2 is overexpressed in cancers (e.g., lung, colorectal) and linked to tumor progression and therapy resistance. Its role in viral replication (e.g., HIV, HBV) and immune dysregulation highlights its therapeutic relevance. ILF2 antibodies aid in elucidating these mechanisms, supporting drug discovery and biomarker development. Validation via knockout controls or mass spectrometry ensures antibody specificity, critical for reliable data. Overall, ILF2 antibodies are vital for exploring its biological and pathological functions.
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