| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | MHC-G |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human HLA-G |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下为3篇关于FABP3抗体的参考文献摘要信息：
1. **文献名称**: "Fatty acid-binding protein 3 (FABP3) is a novel biomarker of cardiac injury"
**作者**: Tanaka T, et al.
**摘要**: 研究验证了FABP3抗体在心肌损伤诊断中的应用，发现FABP3在心肌缺血后快速释放到血液中，可作为早期心肌损伤的生物标志物。抗体通过ELISA和免疫组化检测到其在心脏组织中的特异性表达。
2. **文献名称**: "FABP3 as a potential biomarker for neurodegenerative diseases"
**作者**: Teunissen CE, et al.
**摘要**: 通过Western blot和免疫荧光技术，利用FABP3抗体发现其在阿尔茨海默病患者脑脊液中表达升高，提示其可能参与神经退行性病变的脂质代谢异常。
3. **文献名称**: "Role of FABP3 in cancer cell proliferation and invasion"
**作者**: Liu R, et al.
**摘要**: 研究使用FABP3抗体在乳腺癌细胞系中敲低FABP3.发现其通过调控脂肪酸代谢影响癌细胞增殖和迁移能力，表明FABP3可能成为癌症治疗的潜在靶点。
(注：以上文献信息为基于领域内典型研究的示例性概括，实际引用时需核对原始文献细节。)
Fatty Acid Binding Protein 3 (FABP3), also known as Heart-Type Fatty Acid Binding Protein (H-FABP), is a small cytoplasmic protein involved in intracellular fatty acid transport and metabolism. Primarily expressed in cardiac and skeletal muscle tissues, as well as specific brain regions, FABP3 facilitates the uptake and compartmentalization of long-chain fatty acids, playing a critical role in energy homeostasis. Its expression is tightly regulated under physiological conditions but is markedly elevated during tissue injury, particularly in myocardial infarction, muscular dystrophy, or neurodegenerative disorders like Alzheimer’s disease.
FABP3 antibodies are essential tools for detecting and quantifying FABP3 in research and clinical diagnostics. These antibodies are widely used in techniques such as Western blotting, immunohistochemistry, and ELISA to study FABP3’s expression patterns, cellular localization, and pathological implications. In cardiology, FABP3 serves as an early biomarker for acute myocardial injury due to its rapid release into circulation post-cell damage. Similarly, in neuroscience, altered FABP3 levels are linked to synaptic dysfunction and neurodegeneration.
Commercial FABP3 antibodies are typically raised against recombinant human or murine FABP3 proteins, with validated specificity across species. Researchers prioritize antibodies with high sensitivity and minimal cross-reactivity to other FABP isoforms (e.g., FABP1. FABP4) to ensure accurate results. Ongoing studies continue to explore FABP3’s dual roles in lipid metabolism and disease progression, underscoring the antibody’s utility in both mechanistic research and biomarker development.
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