关键信息
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基因名
ANP32A
- 应用
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别名
LANP; MAPM; PHAP1; C15orf1; Mapmodulin; Leucine-rich acidic nuclear protein; Putative HLA-DR-associated protein I; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A
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种属
Mouse
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
O35381
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表达区间
Glu2-Asp247
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分子量
58/50kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Research on the ANP32A recombinant protein has gained significant attention due to its critical role in various cellular processes, particularly in the regulation of gene expression and chromatin remodeling. ANP32A, a member of the acidic nuclear phosphoprotein 32 family, is involved in the modulation of several key signaling pathways and has been implicated in both normal cellular functions and disease states, including cancer. Its ability to interact with histones and other proteins highlights its potential as a regulatory factor in transcriptional control. Recent studies have shown that ANP32A can influence the activity of histone acetyltransferases and deacetylases, making it an important player in the epigenetic landscape of the cell. Furthermore, the recombinant production of ANP32A allows for detailed biochemical characterization and functional assays, facilitating the exploration of its molecular mechanisms. The development of ANP32A as a recombinant protein not only enables the study of its role in cellular biology but also paves the way for potential therapeutic applications, particularly in targeting aberrant pathways in cancer and other diseases. Overall, the ongoing investigation into ANP32A continues to unveil its multifaceted contributions to cellular homeostasis and offers insights into its broader implications in health and disease.
