Rabbit Monoclonal IRF6 Antibody

The IRF6 (Interferon Regulatory Factor 6) antibody is a key tool for studying the role of IRF6. a transcription factor critical in embryonic development, particularly in craniofacial and epidermal formation. IRF6. part of the interferon regulatory factor family, regulates gene expression involved in cell differentiation, proliferation, and tissue integrity. Mutations in the IRF6 gene are linked to human disorders like Van der Woude syndrome and popliteal pterygium syndrome, characterized by orofacial clefts and skin anomalies. The IRF6 antibody enables detection and localization of IRF6 protein in tissues and cells, aiding research into its molecular mechanisms. It is widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to assess IRF6 expression levels and distribution under physiological or pathological conditions. Studies using this antibody have revealed IRF6's involvement in epithelial-mesenchymal interactions, wound healing, and cancer progression. Additionally, it helps validate experimental models (e.g., knockouts or knock-ins) and screen clinical samples for IRF6 dysregulation. As IRF6 gains attention as a potential therapeutic target, the antibody remains essential for dissecting its roles in development, disease, and regeneration.