关键信息
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基因名
Centrin-2
- 应用
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别名
CALT; CEN2; Caltractin; Centrin EF-Hand Protein 2; Caltractin isoform 1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P41208
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表达区间
Ala2~Leu171
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分子量
24kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Centrin-2 is a member of the centrin protein family, which plays an essential role in various cellular processes, including mitotic spindle formation, centrosome function, and ciliary assembly. It is a calcium-binding protein that is predominantly expressed in ciliated cells and is critical for the structural integrity and function of centrosomes and basal bodies. Research into Centrin-2 has intensified due to its involvement in several cellular mechanisms that influence cell division and signaling pathways. Aberrant functioning of Centrin-2 has been associated with various diseases, including cancer and ciliopathies. Understanding the structure and dynamics of Centrin-2 through recombinant protein studies can provide invaluable insights into its physiological roles and potential implications in disease. Recombinant protein technology facilitates the production of Centrin-2 in a controlled environment, allowing for detailed structural and functional analysis. This research not only aids in deciphering the intricate roles of Centrin-2 in normal cellular operations but also sheds light on the molecular mechanisms underlying diseases linked to its malfunction.
