关键信息
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基因名
CSNK1A1L
- 应用
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别名
CK1
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N752
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表达区间
1-337aa
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分子量
66.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CSNK1A1L, or Casein Kinase 1 Alpha L, is a member of the casein kinase 1 (CK1) family known for its role in various cellular processes, including cell cycle regulation, signal transduction, and circadian rhythms. Recent studies have indicated that CSNK1A1L is involved in crucial signaling pathways, such as the Wnt/β-catenin pathway, which is significant for development and cancer biology. Due to its regulatory functions and implications in diseases, including neurodegenerative disorders and cancers, the recombinant protein of CSNK1A1L has garnered attention for its potential as a therapeutic target. Investigating the biochemical properties and functional mechanisms of CSNK1A1L through recombinant protein studies can offer insights into its roles in cell signaling and disease progression. Moreover, understanding the structure-function relationship of this protein may lead to the identification of small-molecule inhibitors or activators, which could pave the way for novel treatment strategies. Therefore, the production and characterization of CSNK1A1L recombinant protein are essential steps in elucidating its functions and therapeutic potential in various medical contexts.
