| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | RTS; TYMSAS |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human ENOSF1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ENOSF1抗体的3篇假设性参考文献示例(实际文献需通过学术数据库验证)：
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1. **文献名称**: "ENOSF1 as a Novel Biomarker in Colorectal Cancer: Immunohistochemical Analysis Using a Novel Polyclonal Antibody"
**作者**: Smith A, et al.
**摘要**: 本研究开发了一种针对ENOSF1蛋白的多克隆抗体，并通过免疫组化分析发现ENOSF1在结直肠癌组织中显著高表达，提示其作为肿瘤诊断标志物的潜力。
2. **文献名称**: "Functional Characterization of ENOSF1 in Mitochondrial Metabolism via Antibody-mediated Knockdown"
**作者**: Chen L, et al.
**摘要**: 利用ENOSF1特异性抗体进行蛋白质敲低实验，揭示了ENOSF1在线粒体能量代谢中的关键作用，并发现其缺失导致细胞增殖抑制。
3. **文献名称**: "Epitope Mapping of ENOSF1 Antibodies for Structural Analysis"
**作者**: Gupta R, et al.
**摘要**: 通过表位定位技术解析了ENOSF1抗体的结合区域，为开发高特异性诊断工具及研究ENOSF1蛋白构效关系提供了基础。
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**备注**：以上内容为模拟示例，实际文献需通过PubMed、Web of Science等平台检索关键词“ENOSF1 antibody”获取。建议结合具体研究方向筛选近年高引用论文。
The ENOSF1 (Enolase Superfamily Member 1) gene encodes a protein belonging to the enolase superfamily, which is involved in diverse metabolic pathways. While enolases are classically known for their role in glycolysis, ENOSF1 exhibits distinct functional characteristics. It is implicated in catalyzing reactions in specialized pathways, such as the metabolism of small molecules, though its precise biochemical role remains under investigation. Studies suggest ENOSF1 may interact with mitochondrial enzymes, influencing cellular energy homeostasis and oxidative stress responses.
ENOSF1 antibodies are essential tools for detecting and characterizing the protein's expression, localization, and interactions in biological samples. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study ENOSF1's tissue distribution and dysregulation in diseases. For instance, ENOSF1 has been linked to cancer progression, with altered expression observed in colorectal, breast, and gastric cancers, suggesting potential roles as a biomarker or therapeutic target. Additionally, ENOSF1 variants are associated with rare genetic disorders, including mitochondrial encephalopathies, highlighting its importance in cellular metabolism.
Research using ENOSF1 antibodies has advanced understanding of its dual cytoplasmic and mitochondrial localization, hinting at multifaceted roles in cellular physiology. Ongoing studies aim to clarify its molecular mechanisms and therapeutic relevance in metabolic and neoplastic diseases.
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