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产品描述：人血管紧张素Ⅱ受体1(ANGⅡR-1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆、细胞裂解物样本中的AGTR1含量。AGTR1即血管紧张素Ⅱ 1型受体，在人体心血管系统等中发挥重要作用。研究发现它参与血管收缩、醛固酮释放等过程。其异常活动与高血压等疾病密切相关。对AGTR1的研究机制主要聚焦于阻断其活性，研发相关拮抗剂用于疾病治疗。试剂盒检测范围为46.88 pg/mL-3000 pg/mL，适用于心血管疾病机制研究、药物靶点筛选、动物模型评估等科研领域，为探索ANGⅡR - 1在生理调控与病理状态中的作用提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：AG2S ELISA Kit; Agtr 1 ELISA Kit; Agtr1 ELISA Kit; AGTR1_HUMAN ELISA Kit; Agtr1a ELISA Kit; AGTR1B ELISA Kit; Ang II ELISA Kit; Angiotensin II receptor type 1 ELISA Kit; Angiotensin II type-1 receptor ELISA Kit; Angiotensin receptor 1 ELISA Kit; Angiotensin receptor 1B ELISA Kit; AT 1B ELISA Kit; AT 1r ELISA Kit; AT1 ELISA Kit; At1a ELISA Kit; AT1AR ELISA Kit; AT1B ELISA Kit; AT1BR ELISA Kit; AT1R ELISA Kit; AT2R1 ELISA Kit; AT2R1A ELISA Kit; AT2R1B ELISA Kit; HAT1R ELISA Kit; Type 1 angiotensin II receptor ELISA Kit; Type 1B angiotensin II receptor ELISA Kit; Type-1 angiotensin II receptor ELISA Kit
缩写：AGTR1
Uniprot No.：P30556
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates, cell lysates
检测范围：46.88 pg/mL-3000 pg/mL
灵敏度：11.72 pg/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Cardiovascular
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human ANGⅡR-1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 92 | ||||
| Range % | 81-98 | |||||
| 1:2 | Average % | 96 | ||||
| Range % | 93-105 | |||||
| 1:4 | Average % | 94 | ||||
| Range % | 87-98 | |||||
| 1:8 | Average % | 103 | ||||
| Range % | 96-110 | |||||
回收率：
| The recovery of human ANGⅡR-1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 92 | 87-96 | ||||
| EDTA plasma (n=4) | 99 | 90-108 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| pg/mlOD1OD2AverageCorrected30002.3542.2542.3042.15315001.7121.6121.6621.5117501.1311.0811.1060.9553750.5660.5560.5610.410187.50.3380.3280.3330.18293.750.2770.2670.2720.12146.880.2090.2050.2070.05600.1520.1500.151 | ||||||
货期：3-5 working days
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