关键信息
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基因名
West Nile Virus NS1
- 应用
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别名
West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein
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种属
Virus
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
YP_001527881.1
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表达区间
D1-A352
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
West Nile Virus (WNV) is a mosquito-borne flavivirus responsible for significant neurological disease in humans and various other vertebrates. Among the proteins encoded by the WNV genome, the non-structural protein 1 (NS1) plays a critical role in the virus's pathogenesis and immune evasion, making it a target of interest for both research and vaccine development. NS1 is involved in the viral life cycle, modulating the host's immune response, and is secreted in either soluble or membrane-associated forms. Studies have shown that NS1 can elicit an immune response, indicating its potential as a biomarker for infection and a candidate for vaccine formulation. Furthermore, the ability to produce recombinant NS1 protein allows researchers to investigate its biological functions, structure, and interactions with the immune system. Understanding the characteristics of NS1 is essential for developing effective diagnostics and therapeutics against WNV, as well as for elucidating the mechanisms by which this virus alters host immune responses. Given the global spread of WNV and its public health implications, prioritizing research on NS1 and its recombinant forms is crucial for advancing our knowledge and improving strategies for disease prevention and control.
