| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | ASD4 |
| WB Predicted band size | 49 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human TBX20 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于TBX20抗体的3篇参考文献示例(注：以下内容为模拟生成，仅供参考)：
1. **文献名称**: "TBX20 regulates angiogenesis and myocardial growth in early heart development"
**作者**: Smith J, et al.
**摘要**: 本研究利用TBX20特异性抗体，通过免疫组化和Western blot技术，揭示了TBX20在小鼠胚胎心脏发育中调控血管生成和心肌细胞增殖的作用，并证实其表达缺失导致心脏形态异常。
2. **文献名称**: "Altered TBX20 expression in human dilated cardiomyopathy: A comparative study"
**作者**: Zhang L, et al.
**摘要**: 通过免疫荧光染色和蛋白质分析，作者发现扩张型心肌病患者心肌组织中TBX20蛋白水平显著下调，提示其表达异常可能与心脏功能衰退相关。
3. **文献名称**: "TBX20 antibody validation for zebrafish cardiac regeneration models"
**作者**: Tanaka K, et al.
**摘要**: 该研究验证了TBX20抗体在斑马鱼心脏再生模型中的应用，证明其可用于检测损伤后心肌细胞的再分化过程，为再生机制研究提供工具支持。
如需实际文献，建议通过PubMed或Google Scholar检索关键词“TBX20 antibody”或“TBX20 immunohistochemistry”获取最新研究。
The TBX20 antibody is a crucial tool in studying the role of T-box transcription factor 20 (TBX20), a member of the evolutionarily conserved T-box family. TBX20 plays vital roles in embryonic development, particularly in heart morphogenesis, chamber formation, and valve development. It also regulates postnatal cardiac function and is implicated in congenital heart diseases (e.g., septal defects, cardiomyopathy) and certain cancers. The antibody detects TBX20 protein expression, enabling researchers to investigate its spatial-temporal localization, interactions, and regulatory mechanisms in tissues.
Typically produced in hosts like rabbits or mice, TBX20 antibodies are validated for specificity in applications such as Western blotting, immunohistochemistry, and immunofluorescence. Studies using this antibody have revealed TBX20's involvement in signaling pathways (e.g., Wnt, BMP) and its crosstalk with other transcription factors (e.g., GATA4. NKX2-5). Dysregulation of TBX20 is linked to pathological conditions, making the antibody valuable for both basic research and clinical diagnostics. Commercial TBX20 antibodies are often characterized using knockout controls or peptide-blocking assays to ensure reliability. Its utility extends to developmental biology, cardiology, and oncology, highlighting its interdisciplinary importance.
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