关键信息
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基因名
ADAMDEC1
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简介
ADAMDEC1 Protein, Human (HEK293, His) is human recombinant ADAM-like protein decysin-1 (ADAMDEC1) with a 6His tag at the C-terminus.ADAMDEC1 Protein, Human (HEK293, His) is produced by mammalian expression system in human cells.
- 应用
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别名
rHuADAM-like protein decysin-1, His; ADAMDEC-1; ADAM-like protein decysin-1
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15204
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表达区间
K206-E470
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氨基酸序列
KSPEKEDFLRAQKYIDLYLVLDNAFYKNYNENLTLIRSFVFDVMNLLNVIYNTIDVQVALVGMEIWSDGDKIKVVPSASTTFDNFLRWHSSNLGKKIHDHAQLLSGISFNNRRVGLAASNSLCSPSSVAVIEAKKKNNVALVGVMSHELGHVLGMPDVPFNTKCPSGSCVMNQYLSSKFPKDFSTSCRAHFERYLLSQKPKCLLQAPIPTNIMTTPVCGNHLLEVGEDCDCGSPKECTNLCCEALTCKLKPGTDCGGDAPNHTTE
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蛋白长度
Full Length of Mature Protein
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分子量
38.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ADAMDEC1, a member of the ADAM (A Disintegrin and Metalloproteinase) family, is a transmembrane protein known for its role in cell adhesion, migration, and proteolytic activity. It is primarily expressed in dendritic cells and has garnered interest due to its involvement in immune responses and potential implications in inflammatory diseases. Recent studies have shown that ADAMDEC1 can regulate the function of dendritic cells and influence T-cell activation, indicating its crucial role in maintaining immune homeostasis. The expression of ADAMDEC1 is modulated during various pathological conditions, suggesting that it could serve as a biomarker for disease progression or as a therapeutic target. Researchers are increasingly focusing on the recombinant production of ADAMDEC1 protein to investigate its structure-function relationship, functional mechanisms, and potential applications in biomedicine. Understanding this protein's role in immune regulation may pave the way for novel strategies in treating autoimmune diseases, chronic inflammation, and other related disorders, highlighting the importance of further research into ADAMDEC1 and its pathways.
