| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/200 - 1/400 | Human,Mouse,Rat |
| Elisa | 1/10000 | Human,Mouse,Rat |
| Aliases | CLP |
| Entrez GeneID | 23406 |
| clone | 5C8E3 |
| WB Predicted band size | 16kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human COTL1 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是关于COTL1抗体的3篇参考文献概览(文献名为示例性标题,作者为虚拟名称,内容基于典型研究方向整理):
1. **标题**:*COTL1 regulates neutrophil migration via interaction with actin cytoskeleton*
**作者**:Smith A, et al.
**摘要**:研究利用COTL1抗体进行免疫荧光和Western blot实验,发现COTL1通过调控肌动蛋白重塑促进中性粒细胞趋化,为炎症反应机制提供新见解。
2. **标题**:*Coactosin-like protein 1 (COTL1) as a prognostic marker in colorectal cancer*
**作者**:Zhang L, et al.
**摘要**:通过COTL1抗体进行免疫组化分析,证明COTL1在结直肠癌中高表达,且与患者生存率负相关,提示其作为潜在治疗靶点。
3. **标题**:*COTL1 modulates macrophage polarization through NF-κB signaling*
**作者**:Wang Y, et al.
**摘要**:使用COTL1抗体敲低实验,发现COTL1通过NF-κB通路调控巨噬细胞向M1表型极化,影响肿瘤微环境中的免疫应答。
(注:以上为模拟文献,实际文献需通过PubMed、Google Scholar等平台以“COTL1 antibody”或“COTL1 function”为关键词检索获取。)
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