| WB | 1/500 - 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/10000 | Human,Mouse,Rat |
| clone | 3G2E1D9 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Immunogen | Ovalbumin |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇与OVA(卵白蛋白)抗体相关的参考文献示例(内容基于学术文献概括，非真实引用，仅作示例)：
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1. **文献名称**: *"Ovalbumin-specific IgE production in murine models of allergic sensitization"*
**作者**: Fujii H., et al.
**摘要**: 研究探讨了OVA作为过敏原在小鼠模型中诱导IgE抗体反应的机制，分析了Th2细胞极化及IL-4/IL-13信号通路对抗体产生的影响。
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2. **文献名称**: *"Toll-like receptor ligands enhance ovalbumin-specific IgG and IgA antibody responses"*
**作者**: Shimizu T., et al.
**摘要**: 通过比较不同佐剂(如CpG DNA和铝佐剂)对OVA免疫效果的影响，揭示了TLR信号通路如何增强抗原特异性IgG和IgA抗体的生成。
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3. **文献名称**: *"Optimization of OVA immunization protocols for high-titer antibody generation"*
**作者**: Nakamura K., et al.
**摘要**: 系统评估了OVA免疫剂量、频率和佐剂组合对小鼠血清中抗OVA IgG抗体效价的影响，提出标准化免疫方案以提高实验可重复性。
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4. **文献名称**: *"OVA-induced airway inflammation: Role of IgG antibodies in immune modulation"*
**作者**: Berin M.C., et al.
**摘要**: 研究OVA致敏小鼠的气道炎症模型，发现抗原特异性IgG抗体可通过Fcγ受体介导的调控作用减轻Th2型炎症反应。
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(注：以上为模拟文献，实际研究中请通过PubMed或Web of Science检索具体论文。)
Ovalbumin (OVA) antibodies are immunoglobulins generated against ovalbumin, a glycoprotein comprising 50–60% of egg white proteins. As a well-characterized model antigen, OVA is widely used in immunological research due to its stability, ease of purification, and immunogenicity. OVA-specific antibodies are typically produced by immunizing animals (e.g., mice, rabbits) with purified OVA, triggering B-cell activation and antibody secretion. These antibodies belong predominantly to the IgG class and exhibit high affinity for conformational or linear epitopes on OVA.
OVA antibodies serve as critical tools in studying immune responses, allergy mechanisms, and vaccine development. They are employed in techniques like ELISA, Western blotting, and immunohistochemistry to detect OVA in biological samples or to track antigen-specific immune cell interactions. In allergy research, OVA is used to induce hypersensitivity in animal models, with anti-OVA IgE and IgG antibodies serving as markers of sensitization and tolerance.
Additionally, OVA-antibody complexes are utilized in antigen-presentation studies, helping elucidate T-cell activation pathways. Their standardized availability and reproducibility make OVA antibodies a cornerstone in experimental immunology, bridging basic research and therapeutic applications, such as evaluating drug efficacy or dendritic cell-based therapies.
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