Cat: PA2000-7912

Recombinant Human GATAD2A Protein,His

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关键信息

  • 基因名

    GATAD2A

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    FLJ20085; FLJ21017; GATA zinc finger domain containing 2A; GATA zinc finger domain containing protein 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66 alpha; Hp66alpha; OTTHUMP00000201911; OTTHUMP00000201912; P66 alpha; P66A_HUMAN

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q86YP4

  • 表达区间

    1-633aa

  • 氨基酸序列

    MTEEACRTRS QKRALERDPT EDDVESKKIK MERGLLASDL NTDGDMRVTP EPGAGPTQGL LRATEATAMA MGRGEGLVGD GPVDMRTSHS DMKSERRPPS PDVIVLSDNE QPSSPRVNGL TTVALKETST EALMKSSPEE RERMIKQLKE ELRLEEAKLV LLKKLRQSQI QKEATAQKPT GSVGSTVTTP PPLVRGTQNI PAGKPSLQTS SARMPGSVIP PPLVRGGQQA SSKLGPQASS QVVMPPLVRG AQQIHSIRQH SSTGPPPLLL APRASVPSVQ IQGQRIIQQG LIRVANVPNT SLLVNIPQPT PASLKGTTAT SAQANSTPTS VASVVTSAES PASRQAAAKL ALRKQLEKTL LEIPPPKPPA PEMNFLPSAA NNEFIYLVGL EEVVQNLLET QGRMSAATVL SREPYMCAQC KTDFTCRWRE EKSGAIMCEN CMTTNQKKAL KVEHTSRLKA AFVKALQQEQ EIEQRLLQQG TAPAQAKAEP TAAPHPVLKQ VIKPRRKLAF RSGEARDWSN GAVLQASSQL SRGSATTPRG VLHTFSPSPK LQNSASATAL VSRTGRHSER TVSAGKGSAT SNWKKTPLST GGTLAFVSPS LAVHKSSSAV DRQREYLLDM IPPRSIPQSA TWK

  • 分子量

    68.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

GATAD2A (GATA Zinc Finger Domain Containing Protein 2A) is a critical gene encoding a protein that plays a pivotal role in various biological processes, including transcription regulation, apoptosis, and cellular differentiation. Its function is mainly attributed to its involvement in chromatin remodeling and the regulation of gene expression, which is essential for normal development and cellular homeostasis. Research has shown that GATAD2A is associated with several diseases, including cancers and neurodegenerative disorders, making it a potential biomarker and therapeutic target. The study of GATAD2A recombinant protein is vital for elucidating its molecular mechanisms and interactions with other proteins and DNA. By producing and purifying GATAD2A as a recombinant protein, researchers can investigate its structural properties and functional assays to better understand how it influences gene expression and cellular processes. Additionally, dissecting the signaling pathways modulated by GATAD2A can provide insights into its role in disease states, offering avenues for targeted therapies. Overall, the investigation of GATAD2A and its recombinant protein holds promise for advancing our awareness of both fundamental biology and the pathological mechanisms underlying various diseases.

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