关键信息
-
基因名
TAIP-2
- 应用
-
别名
CSRNP3; FAM130A2; TAIP2Cysteine/serine-rich nuclear protein 3; CSRNP-3; Protein FAM130A2; TGF-beta-induced apoptosis protein 2; TAIP-2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8WYN3
-
表达区间
1-585 aa
-
氨基酸序列
MSGILKRKFE EVDGSSPCSS VRESDDEVSS SESADSGDSV NPSTSSHFTP SSILKREKRL RTKNVHFSCV TVYYFTRRQG FTSVPSQGGS TLGMSSRHNS VRQYTLGEFA REQERLHREM LREHLREEKL NSLKLKMTKN GTVESEEAST LTLDDISDDD IDLDNTEVDE YFFLQPLPTK KRRALLRASG VKKIDVEEKH ELRAIRLSRE DCGCDCRVFC DPDTCTCSLA GIKCQVDRMS FPCGCTKEGC SNTAGRIEFN PIRVRTHFLH TIMKLELEKN REQQIPTLNG CHSEISAHSS SMGPVAHSVE YSIADSFEIE TEPQAAVLHL QSAEELDCQG EEEEEEEDGS SFCSGVTDSS TQSLAPSESD EEEEEEEEEE EEEDDDDDKG DGFVEGLGTH AEVVPLPSVL CYSDGTAVHE SHAKNASFYA NSSTLYYQID SHIPGTPNQI SENYSERDTV KNGTLSLVPY TMTPEQFVDY ARQAEEAYGA SHYPAANPSV IVCCSSSEND SGVPCNSLYP EHRSNHPQVE FHSYLKGPSQ EGFVSALNGD SHISEHPAEN SLSLAEKSIL HEECIKSPVV ETVPV
-
分子量
64.9kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
TAIP-2 (TGF-beta-Accepting Integrin Protein 2) is a novel recombinant protein that has garnered attention in biomedical research due to its potential role in modulating immune responses and its implications in various diseases, including cancer and autoimmune disorders. The protein is part of the larger TGF-beta signaling pathway, which is crucial for regulating cell growth, differentiation, and apoptosis. Abnormalities in this pathway have been linked to tumor progression and immune system dysregulation. Recent studies have indicated that TAIP-2 may serve as a key player in enhancing the efficacy of immune checkpoint therapies by promoting anti-tumor immunity. Researchers are investigating its mechanistic pathways to better understand how TAIP-2 interacts with immune cells and tumor microenvironments. This research aims to leverage the therapeutic potential of TAIP-2, not only as a biomarker for disease progression but also as a possible candidate for novel immunotherapies. As the understanding of its function and applications expands, TAIP-2 could play a significant role in developing targeted treatments for patients with various malignancies and immune-related conditions.
