| 经过测试的应用 | |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 反应物种 | Mouse |
| SwissProt ID | P10749 |
| 抗体类型 | Monoclonal Antibody |
| 克隆性 | Monoclonal |
| 宿主 | Rabbit |
| 基因名 | Il1b |
| 背景信息 | Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. |
| 形式 | Liquid |
| 存储缓冲液 | 0.01M PBS, pH 7.2 |
| 储存 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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