关键信息
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基因名
XRP2
- 应用
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别名
XRP2；Protein XRP2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75695
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表达区间
1-350aa
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氨基酸序列
GCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVLFAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI
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分子量
66.5kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
XRP2, a recombinant protein derived from the X protein of the Epstein-Barr virus (EBV), has garnered significant attention in the field of virology and immunology due to its potential role in viral pathogenesis and host immune responses. EBV is known for its association with various lymphoproliferative disorders and has a complex interaction with the immune system, making it a critical subject of study. The XRP2 protein specifically is implicated in the modulation of immune responses, potentially influencing the development of EBV-related diseases. Researchers are particularly interested in how XRP2 can alter the host's adaptive immune mechanisms, including its impact on T cell activation and cytokine production. Understanding the functional dynamics of XRP2 not only provides insights into the viral life cycle but also has broader implications for vaccine development and therapeutic interventions against EBV-associated malignancies. In recent studies, recombinant XRP2 has been produced and characterized, paving the way for exploring its immunogenic properties and interactions with host cells. This research is crucial for developing strategies to enhance immune responses against EBV and for creating effective treatments for EBV-related diseases, thereby addressing a significant public health challenge.
