关键信息
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基因名
PXMP3
- 应用
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别名
PEX2; PAF1; PMP3; PMP35; PXMP3; RNF72; Peroxisome biogenesis factor 2; 35 kDa peroxisomal membrane protein; Peroxin-2; Peroxisomal membrane protein 3; Peroxisome assembly factor 1; PAF-1; RING finger protein 72
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P28328
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表达区间
1-305 aa
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氨基酸序列
MASRKENAKSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKACLWVFLWRFTIYSKNATVGQSVLNIKYKNDFSPNLRYQPPSKNQKIWYAVCTIGGRWLEERCYDLFRNHHLASFGKVKQCVNFVIGLLKLGGLINFLIFLQRGKFATLTERLLGIHSVFCKPQNIREVGFEYMNRELLWHGFAEFLIFLLPLINVQKLKAKLSSWCIPLTGAPNSDNTLATSGKECALCGEWPTMPHTIGCEHIFCYFCAKSSFLFDVYFTCPKCGTEVHSLQPLKSGIEMSEVNAL
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分子量
61.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PXMP3 (Peroxisomal Membrane Protein 3) is a crucial component of the peroxisomal membrane and plays an essential role in peroxisome biogenesis and function. Peroxisomes are organelles involved in various metabolic processes, including lipid metabolism and the detoxification of reactive oxygen species. Abnormalities in PXMP3 expression or function have been linked to a range of metabolic disorders and neurodegenerative diseases. Research into the PXMP3 protein involves understanding its structure, membrane localization, and interactions with other proteins that facilitate peroxisome assembly and maintenance. Advances in recombinant protein technology enable the production of PXMP3 in heterologous systems, allowing detailed biochemical and biophysical characterization of its functions. Such studies are critical for uncovering the mechanisms underlying peroxisomal diseases and may aid in the development of therapeutic strategies targeting these metabolic pathways. Understanding the role of PXMP3 in cellular metabolism not only provides insight into fundamental biological processes but also holds potential for novel treatments for diseases associated with peroxisomal dysfunction.
