Cat: IPD-X14082

Recombinant Rat Adiponectin/Acrp30 Protein, N-His

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关键信息

  • 基因名

    Adiponectin/Acrp30

  • 应用

    SPR MST BLI ITC ELISA 细胞实验 药物筛选

  • 别名

    GBP28; ApM1; AdipoQ; Acrp30; ACDC; APM1; C1Q And Collagen Domain Containing; Adipocyte Complement-Related Protein Of 30 KDa; Adipose Most Abundant Gene Transcript 1

  • 种属

    Rat

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 97% as determined by SDS-PAGE.

  • 蛋白编号

    Q8K3R4

  • 表达区间

    Tyr111~Asn244

  • 蛋白长度

    Partial

  • 分子量

    18kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Adiponectin, also known as Acrp30, is a peptide hormone secreted by adipocytes that plays a crucial role in metabolic processes, including insulin sensitivity, glucose regulation, and fatty acid oxidation. Its anti-inflammatory and insulin-sensitizing properties have drawn significant interest in the context of obesity, type 2 diabetes, and cardiovascular diseases. Research has shown that lower levels of adiponectin are associated with obesity-related complications, making it a potential biomarker for metabolic disorders. Recombinant adiponectin/Acrp30 protein has been developed to explore its therapeutic potential in treating metabolic syndromes. Studies investigating the functional aspects of this protein have highlighted its ability to enhance the metabolic profile, improve insulin sensitivity, and reduce inflammation in various animal models. Furthermore, recombinant adiponectin holds promise for clinical applications, including the treatment of insulin-resistant states and obesity-related conditions. As researchers continue to elucidate the mechanisms behind adiponectin's actions, the development and optimization of recombinant forms of this protein may pave the way for novel therapeutic strategies aimed at combating metabolic diseases and improving overall metabolic health.

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