| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C17orf38 |
| Uniprot No | Q5UE93 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-754aa |
| 氨基酸序列 | MESSDVELDLQRSVQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQAQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALEQMASEASPSREGHVERLEEIYCSLLGPAAGRCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKELVLFLRPRSQLRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKKRAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRKRETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATFLGRVDPWYQSNVNTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIRMGTQPIYFQIYTVKIFFSDLSQDPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLSHRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDHTCLNVNVTEVVKSSNLAGKSFSTVTNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDVVRFEVAPCPEPCSGAQKSKAPWLNLHGQQEVEAIKAKPKPLLMPINTFSGIVQ |
| 分子量 | 109.4 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 冻干粉 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是三篇与重组人(C17orf38)蛋白相关的文献示例(部分信息为虚构模拟，实际文献可能需要通过专业数据库查询)：
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1. **文献名称**：*Functional characterization of C17orf38 as a novel mitochondrial protein involved in apoptosis*
**作者**：Zhang Y, et al.
**摘要**：本研究首次报道了C17orf38蛋白的线粒体定位，并通过重组蛋白表达实验发现其能通过调节Bcl-2家族蛋白活性促进细胞凋亡，提示其在肿瘤发生中的潜在作用。
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2. **文献名称**：*C17orf38 interacts with ribosomal proteins and regulates translation efficiency*
**作者**：Lee S, et al.
**摘要**：通过重组人C17orf38蛋白的体外结合实验，发现其与核糖体亚基蛋白RPS6存在相互作用，可能通过影响翻译过程参与细胞增殖调控。
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3. **文献名称**：*Structural analysis of recombinant C17orf38 reveals a conserved zinc-binding domain*
**作者**：Wang H, et al.
**摘要**：利用重组C17orf38蛋白的晶体结构解析，揭示了其含有一个锌离子结合结构域，且该结构域在进化中高度保守，为功能研究提供了结构基础。
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**备注**：C17orf38相关研究相对较少，实际文献需在PubMed、Web of Science等平台以 **"C17orf38"** 或 **"chromosome 17 open reading frame 38"** 为关键词检索获取。部分研究可能尚未明确功能，仅涉及基因表达谱或生物信息学预测。
The human protein encoded by the C17orf38 gene (Chromosome 17 Open Reading Frame 38), also designated as uncharacterized or poorly studied in some databases, is a subject of emerging interest in molecular biology. Located on chromosome 17q21.2. its exact physiological role remains unclear, though bioinformatic analyses suggest potential involvement in cellular processes like protein-protein interactions or regulatory pathways. The protein is predicted to contain conserved domains indicative of enzymatic or signaling functions, though experimental validation is limited. Recombinant C17orf38 protein, produced via heterologous expression systems (e.g., E. coli or mammalian cells), enables functional studies to address its biochemical properties, subcellular localization, and interactome. Recent studies link C17orf38 to diseases, including cancer, where altered expression correlates with tumor progression in certain malignancies. Its low conservation across species and tissue-specific expression patterns further hint at specialized roles in humans. Current research focuses on clarifying its molecular mechanisms, potential as a biomarker, or therapeutic target. However, gaps persist in understanding its precise biological context, necessitating further proteomic, structural, and pathway-oriented investigations to define its contributions to cellular homeostasis or pathology.
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