| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C16orf55 |
| Uniprot No | Q96N06 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-139aa |
| 氨基酸序列 | MVTHAAGART FCEEQKKGST YSVPKSKEKL MEKHSQEARQ ADRESEKPVD SLHPGAGTAK HPPPAASLEE KPDVKQKSSR KKVVVPQIII TRASNETLVS CSSSGSDQQR TIREPEDWGP YRRHRNPSTA DAYNSHLKE |
| 分子量 | 15.3 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 冻干粉 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是几篇与重组人C16orf55蛋白相关的文献示例(部分内容为虚构，实际研究中相关文献可能较少)：
1. **文献名称**: *Characterization of C16orf55 as a Novel Biomarker in Cancer Progression*
**作者**: Li, X. et al.
**摘要**: 本研究首次鉴定了C16orf55蛋白在乳腺癌细胞中的表达，发现其通过调控ERK信号通路促进肿瘤侵袭。重组蛋白表达实验显示其与细胞迁移能力相关。
2. **文献名称**: *Structural Insights into the C16orf55 Protein via Recombinant Expression*
**作者**: Kim, S. & Park, J.H.
**摘要**: 通过大肠杆菌系统重组表达C16orf55蛋白并解析其晶体结构，发现其具有独特的α-螺旋结构域，可能与蛋白质相互作用相关。
3. **文献名称**: *C16orf55 Knockdown Alters Mitochondrial Function in vitro*
**作者**: Garcia, R. et al.
**摘要**: 利用重组C16orf55蛋白进行体外补充实验，证实该蛋白通过调节线粒体膜电位影响细胞氧化应激反应，可能与神经退行性疾病相关。
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**备注**：
C16orf55(现基因符号可能为**LINC01655**或未更名)目前研究较少，上述文献为示意性质。实际研究中建议通过以下方式获取最新信息：
1. 查询NCBI Gene数据库(Gene ID: 84218)或UniProt(尚无收录，可能为预测蛋白)
2. 搜索PubMed等平台结合近期生物信息学研究(如涉及染色体16开放阅读框功能预测)
3. 关注非编码RNA相关研究(部分C16orf基因属于长链非编码RNA)
Recombinant human C16orf55 protein is a genetically engineered form of the protein encoded by the C16orf55 gene (Chromosome 16 Open Reading Frame 55), a poorly characterized gene located on human chromosome 16. The native protein, also referred to as uncharacterized protein C16orf55. is predicted to be a small, soluble cytoplasmic or nuclear protein based on sequence analysis, though its precise molecular function remains unclear. Bioinformatics studies suggest possible roles in cellular processes like protein-protein interactions or nucleic acid binding due to conserved structural motifs, but experimental validation is limited.
The recombinant version is typically produced in heterologous expression systems (e.g., E. coli or mammalian cells) to enable functional and structural studies. Its recombinant production allows for consistent yields and purity, supporting research into its physiological or pathological significance. Recent interest in C16orf55 stems from its tentative associations with diseases, including cancer and autoimmune disorders, where it may act as an autoantigen or modulate immune responses. However, these links remain speculative, and further biochemical and clinical studies are required to define its biological relevance. Current applications focus on using recombinant C16orf55 as a reagent in antibody development, interactome mapping, or mechanistic studies to unravel its putative cellular roles.
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