关键信息
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基因名
RPS4X
- 应用
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别名
RPS4X;CCG2;RPS4;SCAR;Small ribosomal subunit Protein eS4. X isoform
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P62701
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表达区间
2-263aa
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氨基酸序列
ARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE ERDKRLAAKQ SSG
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RPS4X, or Ribosomal Protein S4, X-Linked, is a crucial component of the ribosomal machinery, playing a significant role in protein synthesis. It is encoded by the RPS4X gene located on the X chromosome and is vital for the assembly of ribosomes, which are essential for translating mRNA into proteins. Research into RPS4X has gained attention due to its involvement in various cellular processes and its potential implications in diseases. Mutations or dysregulation of this protein have been linked to specific disorders, including Diamond-Blackfan anemia, a type of blood disorder characterized by the failure of bone marrow to produce sufficient red blood cells. Furthermore, given its X-linked inheritance pattern, alterations in RPS4X can differ between sexes, contributing to an understanding of sex-linked diseases. Studies have utilized recombinant DNA technology to express and purify RPS4X protein in suitable systems, enabling detailed investigations into its structural and functional properties. These studies are critical for elucidating the role of RPS4X in cellular mechanisms and could provide insights into therapeutic approaches for associated medical conditions. Understanding RPS4X's function not only enhances our knowledge of ribosome biology but also provides a framework for exploring the genetic underpinnings of related human diseases.
