关键信息
-
基因名
PPIL2
- 应用
-
别名
PPIL2;RING-type E3 ubiquitin-Protein ligase PPIL2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q13356
-
表达区间
1-520aa
-
氨基酸序列
MGKRQHQKDK MYITCAEYTH FYGGKKPDLP QTNFRRLPFD HCSLSLQPFV YPVCTPDGIV FDLLNIVPWL KKYGTNPSNG EKLDGRSLIK LNFSKNSEGK YHCPVLFTVF TNNTHIVAVR TTGNVYAYEA VEQLNIKAKN FRDLLTDEPF SRQDIITLQD PTNLDKFNVS NFYHVKNNMK IIDPDEEKAK QDPSYYLKNT NAETRETLQE LYKEFKGDEI LAATMKAPEK KKVDKLNAAH YSTGKVSASF TSTAMVPETT HEAAAIDEDV LRYQFVKKKG YVRLHTNKGD LNLELHCDLT PKTCENFIRL CKKHYYDGTI FHRSIRNFVI QGGDPTGTGT GGESYWGKPF KDEFRPNLSH TGRGILSMAN SGPNSNRSQF FITFRSCAYL DKKHTIFGRV VGGFDVLTAM ENVESDPKTD RPKEEIRIDA TTVFVDPYEE ADAQIAQERK TQLKVAPETK VKSSQPQAGS QGPQTFRQGV GKYINPAATK RAAEEEPSTS ATVPMSKKKP SRGFGDFSSW
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PPIL2 (peptidyl-prolyl isomerase-like 2) is a member of the cyclophilin family, which plays a crucial role in protein folding and post-translational modifications. Research into PPIL2 has garnered attention due to its potential implications in various biological processes, including cellular signaling, cell cycle regulation, and responses to stress. Its isomerase activity is essential for the proper conformation of proteins, influencing critical cellular functions. Dysregulation of PPIL2 has been linked to several diseases, including cancer and neurodegenerative disorders, suggesting that it may be a valuable target for therapeutic intervention. Furthermore, PPIL2's interactions with other proteins and involvement in molecular pathways highlight its importance in maintaining cellular homeostasis. Understanding the structure and function of recombinant PPIL2 can provide insights into its role in health and disease, paving the way for research into novel treatments that modulate its activity. By investigating the biochemical properties and potential applications of recombinant PPIL2, researchers aim to elucidate its contribution to various physiological processes and its perturbations in pathological conditions, thereby laying the groundwork for future studies focused on harnessing its therapeutic potential.
