关键信息
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基因名
Lymphotactin/XCL1
- 应用
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别名
ATACC motif chemokine 1Cytokine SCM-1Lymphotaxin;SCM-1-alpha;Small-inducible cytokine C1XC chemokine ligand 1
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P47992
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表达区间
22-114aa
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蛋白长度
Partial
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分子量
14.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Lymphotactin (also known as XCL1) is a chemokine that plays a pivotal role in immune responses, specifically in the migration and activation of lymphocytes. Identified as a member of the C motif chemokine family, XCL1 is produced by activated T cells and is known to attract a unique subset of lymphocytes, including T helper 1 (Th1) cells and dendritic cells, to sites of inflammation or infection. The significance of XCL1 in immunology has garnered research interest due to its potential implications in autoimmune diseases, cancer, and viral infections. The recombinant production of XCL1 protein provides a valuable tool for studying its biological functions, signaling pathways, and interactions with its receptor XCR1. Researchers have aimed to characterize the structural and functional properties of recombinant lymphotactin to better understand its role in immune regulation. Furthermore, therapeutic applications of XCL1, particularly in enhancing immune responses against tumors or modulating inflammatory conditions, are being explored, making it a promising candidate for future interventions in immunotherapy. The study of XCL1 and its recombinant protein is crucial, as it could lead to novel insights into immune modulation and potential therapeutic strategies for a variety of diseases.
