| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Putative cyclin-Y-like protein 3, CCNYL3 |
| WB Predicted band size | 39.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CCNYL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human CCNYL3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CCNYL3 (N-term)抗体的示例参考文献(注：以下为虚构内容，实际文献需通过学术数据库检索确认)：
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1. **文献名称**: *Characterization of a Novel CCNYL3 (N-term) Antibody for Detecting Cyclin Y-Like 3 in Human Tissues*
**作者**: Smith A, et al.
**摘要**: 本研究开发并验证了一种针对CCNYL3蛋白N端结构域的多克隆抗体，用于检测其在多种人类组织中的表达。通过Western blot和免疫组化实验证明该抗体特异性高，可用于研究CCNYL3在细胞周期调控中的作用。
2. **文献名称**: *CCNYL3 Regulates Neuronal Differentiation via Wnt Signaling: Insights from Antibody-Based Assays*
**作者**: Lee B, et al.
**摘要**: 利用CCNYL3 (N-term)抗体研究其在神经元分化中的功能，发现CCNYL3通过调控Wnt/β-catenin通路影响神经干细胞的分化。抗体特异性通过siRNA敲低实验和免疫沉淀验证。
3. **文献名称**: *Development of Monoclonal Antibodies Targeting the N-terminal Domain of CCNYL3 for Cancer Biomarker Studies*
**作者**: Zhang C, et al.
**摘要**: 报道了一种针对CCNYL3 N端的单克隆抗体制备及其在癌症生物标志物研究中的应用。该抗体在肺癌和乳腺癌样本中显示出高灵敏度和特异性，提示CCNYL3可能与肿瘤进展相关。
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如需真实文献，建议通过PubMed、Google Scholar等平台检索关键词“CCNYL3 antibody”或“Cyclin Y-like 3 N-terminal”，并筛选涉及抗体开发或应用的论文。
The CCNYL3 (N-term) antibody is a polyclonal or monoclonal reagent specifically designed to detect the N-terminal region of Cyclin Y-like protein 3 (CCNYL3), a member of the cyclin protein family. Cyclins are key regulators of cell cycle progression, primarily through their interaction with cyclin-dependent kinases (CDKs). While CCNY (Cyclin Y) is well-characterized in Wnt signaling and cell cycle modulation, CCNYL3 remains less studied but shares structural homology with cyclin Y, suggesting potential roles in similar pathways. The N-terminal region targeted by this antibody may encompass critical functional domains involved in protein-protein interactions or substrate recognition.
This antibody is commonly used in applications such as Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to investigate CCNYL3 expression, localization, and regulation in various biological contexts, including cancer research, developmental biology, and cellular proliferation studies. Its specificity for the N-terminus ensures minimal cross-reactivity with other cyclin family members. Validation typically includes testing in knockout cell lines or tissues to confirm signal absence, alongside positive controls. Researchers leverage this tool to explore CCNYL3's putative roles in disease mechanisms, transcriptional regulation, or as a biomarker, contributing to broader insights into cell cycle dysregulation pathologies.
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