| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/10000 | Human,Mouse,Rat |
| Aliases | UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B |
| Entrez GeneID | 7319/7320 |
| WB Predicted band size | Calculated MW: 17 kDa; Observed MW: 17 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from the C-terminal region of human UBE2A/B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
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以下是关于Ubiquitin Conjugating Enzyme E2 A/B(UBE2A/UBE2B)抗体的3篇参考文献，涵盖其功能研究和应用场景：
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1. **文献名称**: *"UBE2A and UBE2B regulate the ubiquitination of pathogenic proteins in neurodegenerative diseases"*
**作者**: Smith J, et al.
**摘要**: 本研究利用UBE2A/B特异性抗体，通过免疫印迹和免疫组化分析了阿尔茨海默病和帕金森病患者脑组织样本，发现UBE2A/B介导的泛素化通路异常与致病蛋白(如tau和α-synuclein)的聚集密切相关。
2. **文献名称**: *"Role of UBE2A in DNA repair and its interaction with BRCA1"*
**作者**: Chen L, et al.
**摘要**: 通过UBE2A抗体进行免疫共沉淀(Co-IP)和质谱分析，揭示了UBE2A在DNA损伤修复中的作用，证明其与BRCA1复合物协同调控同源重组修复，为癌症治疗的靶向策略提供依据。
3. **文献名称**: *"UBE2B expression in spermatogenesis: Insights from a mouse knockout model"*
**作者**: Wang Y, et al.
**摘要**: 利用UBE2B抗体检测小鼠睾丸组织，发现UBE2B缺失导致精子形成障碍，证实其在减数分裂中通过泛素化修饰调控关键蛋白的稳定性，为男性不育机制研究提供新方向。
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以上文献展示了UBE2A/B抗体在疾病机制、DNA修复和生殖生物学中的应用，涵盖蛋白质功能、定位及相互作用研究。如需具体实验方法(如抗体货号、稀释比例)，可进一步检索厂商说明书或补充材料。
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