关键信息
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基因名
MCP-5/CCL12
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简介
The MCP-5/CCL12 protein belongs to the intercrine beta family and is essential for chemokines involved in intercellular communication and immune responses. In this family, MCP-5/CCL12 may play a role in regulating inflammatory processes and cellular interactions. MCP-5/CCL12 Protein, Rat is the recombinant rat-derived MCP-5/CCL12 protein, expressed by E. coli , with tag free.
- 应用
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别名
C-C motif chemokine; CCL12
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种属
Rat
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9QZU1
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表达区间
G14-A81
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蛋白长度
Full Length of Mature Protein (with Propeptide)
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分子量
9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MCP-5, also known as CCL12, is a chemokine belonging to the CC (C-C) subfamily that plays a crucial role in immune responses and inflammation. It is primarily involved in the recruitment of monocytes and other immune cells to sites of tissue injury and inflammation. Research on MCP-5/CCL12 has gained importance due to its potential implications in various pathological conditions, including cancer, cardiovascular diseases, and chronic inflammatory disorders. Elevated levels of MCP-5/CCL12 have been linked to disease progression and severity, making it a target for therapeutic intervention. Scientists have focused on producing recombinant MCP-5/CCL12 protein to study its biological functions, signaling pathways, and potential as a biomarker for disease. Recombinant proteins enable the detailed investigation of MCP-5/CCL12 in vitro and in vivo, thus facilitating the understanding of its role in the immune response. Additionally, insights gained from MCP-5/CCL12 studies can pave the way for developing novel therapies aimed at modulating immune responses in various diseases, highlighting its significance in both basic and clinical research.
