关键信息
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基因名
PDCD2L
- 应用
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别名
PDCD2L; Programmed cell death protein 2-like
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BRP1
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表达区间
1-358aa
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分子量
66.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PDCD2L, or Programmed Cell Death 2-Like, is a protein belonging to the PDCD2 family, which is implicated in various cellular processes, including apoptosis and cell cycle regulation. Recent research has highlighted its potential role in cancer biology, particularly in how it may affect tumor growth and response to therapy. As a repressor, PDCD2L can influence gene expression by modulating transcription factors and other regulatory proteins, making it a significant factor in cellular homeostasis and regulatory networks. Studies have shown that PDCD2L expression levels can vary across different tissues and conditions, indicating its potential as a biomarker for certain diseases. The recombinant expression of PDCD2L proteins facilitates detailed functional studies, which are crucial for understanding its role in health and disease. By generating PDCD2L in a recombinant system, researchers can investigate its biochemical properties, interactions with other proteins, and functional outcomes in various cellular contexts. This knowledge could lead to the development of novel therapeutic strategies targeting PDCD2L or its pathways, offering new avenues for cancer treatment and improving our understanding of programmed cell death mechanisms.
