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Human Fragile X mental retardation 1 protein(FMR1) ELISA kit

  • 中文名： 人脆性X智力低下蛋白1(FMR1)酶联免疫试剂盒
货号: IPD-EL008756HU
Price： ￥2500
数量：
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产品详情

  • 产品描述：人脆性X智力低下蛋白1(FMR1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的FMR1含量。FMR1 基因是与脆性 X 综合征相关的关键靶点。其突变会导致 FMRP 蛋白表达异常。研究机制主要围绕 FMRP 在神经元发育、突触可塑性等方面的作用，探索其如何影响神经系统功能，为脆性 X 综合征等疾病的治疗提供关键线索。试剂盒检测范围为15.6 pg/mL-1000 pg/mL，适用于神经退行性疾病机制研究、遗传性智力障碍模型构建及神经细胞功能探索等科研场景。该产品为研究FMR1蛋白在神经系统疾病中的表达调控及其分子互作机制提供可靠工具，适用于分子生物学、神经科学等基础研究领域。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。

  • 别名：FMR 1 ELISA Kit; Fmr1 ELISA Kit; Fmr1 gene ELISA Kit; FMR1_HUMAN ELISA Kit; FMRP ELISA Kit; Fragile X mental retardation 1 ELISA Kit; Fragile X mental retardation 1 protein ELISA Kit; Fragile X mental retardation protein 1 ELISA Kit; Fragile X mental retardation protein ELISA Kit; fragile X mental retardation syndrome-related protein 1 ELISA Kit; fragile X mental retardation; autosomal homolog 1 ELISA Kit; FRAXA ELISA Kit; fxr1 ELISA Kit; MGC87458 ELISA Kit; POF ELISA Kit; POF1 ELISA Kit; Protein FMR-1 ELISA Kit; Protein FMR1 ELISA Kit; wu:fb16f11 ELISA Kit; wu:fd18c10 ELISA Kit; zgc:66226 ELISA Kit

  • 缩写：FMR1

  • Uniprot No.：Q06787

  • 种属：Homo sapiens (Human)

  • 样本类型：serum, plasma, tissue homogenates

  • 检测范围：15.6 pg/mL-1000 pg/mL

  • 灵敏度：3.9 pg/mL

  • 反应时间：1-5h

  • 样本体积：50-100ul

  • 检测波长：450 nm

  • 研究领域：Signal Transduction

  • 测定原理：quantitative

  • 测定方法：Sandwich

  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%


    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%


    Three samples of known concentration were tested in twenty assays to assess.








  • 线性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of human FMR1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    		SampleSerum(n=4)
    1:1Average %89
    Range %85-93
    1:2Average %107
    Range %99-111
    1:4Average %92
    Range %85-95
    1:8Average %99
    Range %91-103

  • 回收率：

    The recovery of human FMR1 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5)9185-95
    EDTA plasma (n=4)9890-101














  • 标准曲线：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected 10002.5542.5222.5382.399 5002.0342.0082.0211.882 2501.3851.3671.3761.237 1250.8710.8540.8630.724 62.50.5560.5660.5610.422 31.20.3520.3670.3600.221 15.60.2640.2590.2620.123 00.1410.1370.139  






  • 货期：3-5 working days

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