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产品描述：人骨成型蛋白受体1A(BMPR-1A)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆、细胞裂解物样本中的BMPR1A含量。BMPR1A是重要靶点。它属于骨形态发生蛋白受体，在细胞生长、分化等生理过程中发挥关键作用。研究发现其信号通路异常与多种疾病相关，如某些癌症。通过深入研究它的作用机制，有望为相关疾病的治疗开发新的策略与药物。试剂盒检测范围为0.312 ng/mL-20 ng/mL，适用于体外检测哺乳动物来源样本中BMPR - 1A的表达水平，可为骨形成机制研究、干细胞定向分化实验、组织修复模型构建等基础科研提供可靠数据支持。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：10q23del ELISA Kit; Activin A receptor type II like kinase 3 ELISA Kit; Activin receptor like kinase 3 ELISA Kit; Activin receptor-like kinase 3 ELISA Kit; ACVRLK 3 ELISA Kit; ACVRLK3 ELISA Kit; ALK 3 ELISA Kit; ALK-3 ELISA Kit; ALK3 ELISA Kit; BMP type-1A receptor ELISA Kit; BMPR 1A ELISA Kit; Bmpr ELISA Kit; BMPR-1A ELISA Kit; Bmpr1a ELISA Kit; BMR1A_HUMAN ELISA Kit; Bone morphogenetic protein receptor type IA ELISA Kit; Bone morphogenetic protein receptor type IA precursor ELISA Kit; Bone morphogenetic protein receptor type-1A ELISA Kit; BR 1a ELISA Kit; BR1a ELISA Kit; CD 292 ELISA Kit; CD292 ELISA Kit; CD292 antigen ELISA Kit; EC 2.7.11.30 ELISA Kit; Serine threonine protein kinase receptor R5 ELISA Kit; Serine threonine protein kinase receptor R5 precursor ELISA Kit; Serine/threonine-protein kinase receptor R5 ELISA Kit; SKR 5 ELISA Kit; SKR5 ELISA Kit; zBMPR IA ELISA Kit; zBMPRIA ELISA Kit
缩写：BMPR1A
Uniprot No.：P36894
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates, cell lysates
检测范围：0.312 ng/mL-20 ng/mL
灵敏度：0.078 ng/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Cardiovascular
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human BMPR-1A in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 86 | ||||
| Range % | 81-94 | |||||
| 1:2 | Average % | 95 | ||||
| Range % | 87-98 | |||||
| 1:4 | Average % | 95 | ||||
| Range % | 89-99 | |||||
| 1:8 | Average % | 93 | ||||
| Range % | 86-97 | |||||
回收率：
| The recovery of human BMPR-1A spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 96 | 91-102 | ||||
| EDTA plasma (n=4) | 89 | 83-94 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| ng/mlOD1OD2AverageCorrected202.8642.7242.7942.649102.1212.0282.0751.93051.1541.2251.1901.0452.50.6040.6130.6090.4641.250.3320.3160.3240.1790.6250.2450.2510.2480.1030.3120.2120.2090.2110.06600.1460.1440.145 | ||||||
货期：3-5 working days
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