关键信息
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基因名
PLXDC2
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简介
The PLXDC2 protein is associated with tumor angiogenesis, suggesting its potential role in blood vessel growth in the tumor microenvironment. The specific mechanism and downstream signaling pathways by which PLXDC2 promotes tumor angiogenesis need to be further elucidated, thus prompting people to explore its role in promoting vascularization during tumorigenesis. PLXDC2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PLXDC2 protein, expressed by HEK293 , with C-6*His labeled tag.
- 应用
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生物活性
Immobilized Mouse PLXDC2 at 2 μg/mL or 5 μg/mL (100 μL/well) can bind Anti-PLXDC2 Antibody, The ED50 for this effect is 0.4-1.749 μg/mL. Immobilized Mouse PLXDC2 at 2 μg/mL (100 μL/well) can bind Anti-PLXDC2 Antibody, The ED50 for this effect is 1.749 μg/mL.
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别名
Plexin domain-containing protein 2; Tumor endothelial marker 7-related protein; Plxdc2; Tem7r
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种属
Mouse
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9DC11
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表达区间
E31-A455
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氨基酸序列
EPGHHTNDWIYEVTNAFPWNEEGVEVDSQAYNHRWKRNVDPFKAVDTNRASMGQASPESKGFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPADSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLNEVTVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNGCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEEVQSKEKMCEKTEPGETSQTTTTSHTTTMQFRVLTTTRRAVTSQMPTSLPTEDDTKIALHLKDSGASTDDSAAEKKGGTLHA
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蛋白长度
Extracellular Domain
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分子量
70-96 kDa.
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PLXDC2, or Plexin Domain Containing 2, is a member of the plexin family of proteins known to play crucial roles in various biological processes, including cell signaling, migration, and proliferation. Emerging research has highlighted PLXDC2's significant involvement in neuronal development and function, as well as its potential implications in cancer biology and immune responses. Its reorganization during cell interactions and signaling pathways suggests that PLXDC2 may act as a critical mediator in cellular communication and tissue dynamics. The study of PLXDC2 recombinant proteins has gained traction as scientists aim to elucidate its structure-function relationships and define its roles in pathological conditions. By employing recombinant DNA technology, researchers are capable of producing PLXDC2 in a purified form, allowing detailed biochemical and functional analyses. This approach has opened up avenues for exploring its potential as a therapeutic target, as well as its utility as a biomarker in various diseases. The increasing interest in PLXDC2 provides a promising frontier in understanding complex cellular mechanisms and developing innovative strategies for disease intervention.
